Adenoviruses in medicine: innocuous pathogen, predator, or partner

KM MacNeil, MJ Dodge, AM Evans, TM Tessier… - Trends in molecular …, 2023 - cell.com
The consequences of human adenovirus (HAdV) infections are generally mild. However,
despite the perception that HAdVs are harmless, infections can cause severe disease in …

Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

PC Matthews, C Campbell, O Săndulescu… - Frontiers in …, 2022 - frontiersin.org
During the first half of 2022, the World Health Organization reported an outbreak of acute
severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from …

Pathogenicity and virulence of human adenovirus F41: possible links to severe hepatitis in children

RJ Grand - Virulence, 2023 - Taylor & Francis
Over 100 human adenoviruses (HAdVs) have been isolated and allocated to seven species,
AG. Species F comprises two members-HAdV-F40 and HAdV-F41. As their primary site of …

Pediatric adenovirus pneumonia: clinical practice and current treatment

J Zhang, Y Zhu, Y Zhou, F Gao, X Qiu, J Li… - Frontiers in …, 2023 - frontiersin.org
Adenovirus pneumonia is common in pediatric upper respiratory tract infection, which is
comparatively easy to develop into severe cases and has a high mortality rate with many …

Emerging viral infections in immunocompromised patients: A great challenge to better define the role of immune response

C Agrati, B Bartolini, V Bordoni, F Locatelli… - Frontiers in …, 2023 - frontiersin.org
The immune response to invading pathogens is characterized by the rapid establishment of
a complex network of cellular interactions and soluble signals. The correct balancing of …

Severe acute hepatitis of unknown aetiology in children—what is known?

S Khader, I Foster, A Dagens, A Norton, L Sigfrid - BMC medicine, 2022 - Springer
The ongoing investigations into clusters of children affected by severe acute hepatitis of
unknown aetiology have put our global capacity for a coordinated, effective response to the …

Molecular epidemiology and phylogenetic analyses of human adenovirus in pediatric patients with acute respiratory infections from Hangzhou during COVID-19 …

S Huang, H Wang, L Li, W Xiang, Z Song… - Frontiers in Pediatrics, 2023 - frontiersin.org
Background Acute Respiratory Infections (ARIs) are a major cause of morbidity and mortality
worldwide. Human Adenovirus (HAdV), responsible for 5%–10% of children's ARIs, is one of …

[HTML][HTML] Construction and application of adenoviral vectors

H Zhang, H Wang, Y An, Z Chen - Molecular Therapy. Nucleic …, 2023 - ncbi.nlm.nih.gov
Adenoviral vectors have been widely used as vaccine candidates or potential vaccine
candidates against infectious diseases due to the convenience of genome manipulation …

Acute, severe hepatitis of unknown origin: should we really be afraid of another obscure enemy of our children?

M Aricò, D Caselli - Pediatric Reports, 2022 - mdpi.com
On 31 March 2022, Public Health Scotland was alerted to five children aged 3–5 years,
presenting to the Glasgow children's hospital with severe hepatitis of unknown etiology …

[HTML][HTML] Gastrointestinal tract and viral pathogens

GSK Jagirdhar, YS Pulakurthi… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Viral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract,
causing inflammation and irritation of the lining of the stomach and intestines. Common …