Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic
kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …

Pheochromocytoma and paraganglioma (PPGL) require prompt consideration and efficient
diagnosis and treatment to minimize associated morbidity and mortality. Once considered …

In recent years, the focus of interest on the role of the renin-angiotensin system (RAS) in the
pathophysiology of hypertension and organ injury has changed to a major emphasis on the …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

People with type 1 and type 2 diabetes are at risk of developing progressive chronic kidney
disease (CKD) and end-stage kidney failure. Hypertension is a major, reversible risk factor …

During the past 2 decades, results of both basic science and clinical studies have changed
the physicians' views about adipocyte pathophysiology. Since leptin was discovered in …

Acute kidney injury (AKI) has become an increasing concern for patients due to the
widespread clinical use of nephrotoxic drugs. Currently, the early diagnosis of AKI is still …

Chronic kidney disease (CKD) is associated with high mortality rates and heavy economic
and social burdens. Nearly 10% of the United States population suffer from CKD, with fatal …

Sleep disorders have a profound and well-documented impact on overall health and quality
of life in the general population. In patients with chronic disease, sleep disorders are more …

Despite the high prevalence and enormous public health implications of chronic kidney
disease (CKD), the factors responsible for its development and progression are incompletely …