Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging
SKT Que, FO Zwald, CD Schmults - Journal of the American Academy of …, 2018 - Elsevier
Cutaneous squamous cell carcinoma (cSCC), a malignant proliferation of cutaneous
epithelium, represents 20% to 50% of skin cancers. Although the majority of cSCCs are …
epithelium, represents 20% to 50% of skin cancers. Although the majority of cSCCs are …
Approved antiviral drugs over the past 50 years
E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Cancer immunotherapy: the beginning of the end of cancer?
S Farkona, EP Diamandis, IM Blasutig - BMC medicine, 2016 - Springer
These are exciting times for cancer immunotherapy. After many years of disappointing
results, the tide has finally changed and immunotherapy has become a clinically validated …
results, the tide has finally changed and immunotherapy has become a clinically validated …
The MRE11–RAD50–NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair
Genomic instability in disease and its fidelity in health depend on the DNA damage
response (DDR), regulated in part from the complex of meiotic recombination 11 homolog 1 …
response (DDR), regulated in part from the complex of meiotic recombination 11 homolog 1 …
Human papillomavirus molecular biology and disease association
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …
themselves in a range of different animal species including humans. Viruses that have co …
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
Integration of human papillomavirus (HPV) DNA into the human genome is considered as a
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
The biology and life-cycle of human papillomaviruses
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
Landscape of genomic alterations in cervical carcinomas
AI Ojesina, L Lichtenstein, SS Freeman, CS Pedamallu… - Nature, 2014 - nature.com
Cervical cancer is responsible for 10–15% of cancer-related deaths in women worldwide,.
The aetiological role of infection with high-risk human papilloma viruses (HPVs) in cervical …
The aetiological role of infection with high-risk human papilloma viruses (HPVs) in cervical …
Soluble PD-1: predictive, prognostic, and therapeutic value for cancer immunotherapy
M Khan, Z Zhao, S Arooj, Y Fu, G Liao - Frontiers in immunology, 2020 - frontiersin.org
Programmed death protein 1 (PD-1) interaction with PD-L1 deliver immunosuppressive
environment for tumor growth, and its blockade with directed monoclonal antibodies (anti …
environment for tumor growth, and its blockade with directed monoclonal antibodies (anti …