Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …

Benzodiazepines (BZDs) remain important agents in the management of epilepsy. They are
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …

Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …

The aim of the present study was to investigate the feasibility of the inclusion of a water-
insoluble drug (diazepam, DZ) into solid lipid nanoparticles (SLNs), which offer combined …

Antiepileptic drugs (AEDs) can have both beneficial and adverse psychotropic effects. They
act on neurotransmitter systems, neuronal ion permeability and other targets, although the …

Purpose of review The aim of the study was to provide an overview of the prevalence, risk
factors, burden, and current and emerging pharmacologic treatments for seizure clusters in …

Febrile seizures are the most common seizures seen in children younger than 5 years old.
Out-of-hospital and emergency department providers need to be familiar with the principles …

Background To evaluate safety and tolerability of long-term treatment with diazepam nasal
spray (Valtoco) for seizure clusters in patients aged six to 17 years. Methods The study …

The patient with status epilepticus has continuous or rapidly repeating seizures. Generalised
convulsive status epilepticus (GCSE) is the most common form of the disorder and is a life …

Although most febrile seizures do no harm and two-thirds of initial cases have no witnessed
recurrence, the seizures cause much family anxiety, and are sometimes prolonged. In rare …