C3 glomerulopathy: pathogenesis and treatment
SB Ahmad, AS Bomback - Advances in Chronic Kidney Disease, 2020 - Elsevier
C3 glomerulopathy (C3G) is a rare set of kidney diseases with 2 patterns: C3
glomerulonephritis (C3GN) and dense deposit disease. Pathogenesis of both diseases is …
glomerulonephritis (C3GN) and dense deposit disease. Pathogenesis of both diseases is …
[HTML][HTML] Complement and coagulation crosstalk–Factor H in the spotlight
M Heurich, G McCluskey - Immunobiology, 2023 - Elsevier
The immune complement and the coagulation systems are blood-based proteolytic
cascades that are activated by pathway-specific triggers, based on protein–protein …
cascades that are activated by pathway-specific triggers, based on protein–protein …
[HTML][HTML] Diagnostic and prognostic comparison of immune-complex-mediated membranoproliferative glomerulonephritis and C3 glomerulopathy
M Kovala, M Seppälä, A Räisänen-Sokolowski, S Meri… - Cells, 2023 - mdpi.com
Membranoproliferative glomerulonephritis (MPGN) is subdivided into immune-complex-
mediated glomerulonephritis (IC-MPGN) and C3 glomerulopathy (C3G). Classically, MPGN …
mediated glomerulonephritis (IC-MPGN) and C3 glomerulopathy (C3G). Classically, MPGN …
[HTML][HTML] Overview on the role of complement-specific autoantibodies in diseases
AT Matola, M Józsi, B Uzonyi - Molecular Immunology, 2022 - Elsevier
The complement system is recognized as a major pathogenic or contributing factor in an
ever-growing number of diseases. In addition to inherited factors, autoantibodies to …
ever-growing number of diseases. In addition to inherited factors, autoantibodies to …
Mycoplasma pneumoniae Infection Associated C3 Glomerulopathy Presenting as Severe Crescentic Glomerulonephritis
L De Silva, D Jayasinghe… - Case Reports in …, 2021 - Wiley Online Library
C3 glomerulopathy (C3GP) is a group of diseases caused by a deregulated complement
system, which encompasses both dense deposit disease and C3 glomerulonephritis. Renal …
system, which encompasses both dense deposit disease and C3 glomerulonephritis. Renal …
Complement as new immunotherapy target: past, present, and future
The complement system, an important component of innate immunity, functions as a first-line
host defense in the prevention of microbial infections, clearance of immune complexes, and …
host defense in the prevention of microbial infections, clearance of immune complexes, and …
[HTML][HTML] Diverse clinical presentations of C3 Dominant glomerulonephritis
C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic
immune complex membranoproliferative glomerulonephritis (iMPGN). It is increasingly …
immune complex membranoproliferative glomerulonephritis (iMPGN). It is increasingly …
[HTML][HTML] Endocarditis-Associated C3-Dominant Glomerulonephritis in a Patient With a Solitary Kidney
L Chowdhury, A Alobaidi, I Lytvak - Cureus, 2022 - ncbi.nlm.nih.gov
Infective endocarditis (IE) is still seen globally with acute kidney injuries remaining a
common complication of the disease. Histological specimens often display either diffuse or …
common complication of the disease. Histological specimens often display either diffuse or …
Biologics and Biosimilars: Potential Therapeutics for Autoimmune Renal Diseases
Autoimmune renal diseases are a group of chronic renal disorders due to dysfunction of the
host immune system with similar immunopathological characteristics of occurrence of …
host immune system with similar immunopathological characteristics of occurrence of …
[HTML][HTML] Effectiveness of Cyclosporine in a 10-year-old Girl with C3 Glomerulopathy
KM Jang, YH Park - Childhood Kidney Diseases, 2017 - chikd.org
Abstract C3 glomerulopathy (C3G) is a recently defined pathological entity characterized by
C3 accumulation with absent or scant immunoglobulin deposition, leading to variable …
C3 accumulation with absent or scant immunoglobulin deposition, leading to variable …