Cognitive and motor outcomes of children with prenatal opioid exposure: a systematic review and meta-analysis

SL Yeoh, J Eastwood, IM Wright, R Morton… - JAMA network …, 2019 - jamanetwork.com
Importance Prenatal opioid exposure (POE) is one of the fastest-growing global health
problems, but its association with long-term neurologic and physical development remains …

[HTML][HTML] Prenatal exposure to methadone or buprenorphine and long-term outcomes: a meta-analysis

JM Andersen, G Høiseth, E Nygaard - Early human development, 2020 - Elsevier
Aim To combine meta-analyses of multiple long-term outcomes in children prenatally
exposed to methadone or buprenorphine through their mothers' Opioid maintenance …

Prenatal exposure to methadone or buprenorphine: early childhood developmental outcomes

K Kaltenbach, KE O'Grady, SH Heil… - Drug and alcohol …, 2018 - Elsevier
Background Methadone and buprenorphine are recommended to treat opioid use disorders
during pregnancy. However, the literature on the relationship between longer-term effects of …

Prenatal opioid exposure: the next neonatal neuroinflammatory disease

LL Jantzie, JR Maxwell, JC Newville… - Brain, behavior, and …, 2020 - Elsevier
The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Infant mortality associated with prenatal opioid exposure

JAK Leyenaar, AP Schaefer, JR Wasserman… - JAMA …, 2021 - jamanetwork.com
Importance Knowledge of health outcomes among opioid-exposed infants is limited,
particularly for those not diagnosed with neonatal opioid withdrawal syndrome (NOWS) …

Opioid use in pregnancy

AL Tobon, E Habecker, A Forray - Current Psychiatry Reports, 2019 - Springer
Abstract Purpose of Review Perinatal opioid use is a major public health problem and is
associated with a number of deleterious maternal and fetal effects. We review recent …

Neonatal abstinence syndrome

M Grossman, A Berkwitt - Seminars in perinatology, 2019 - Elsevier
Neonates exposed prenatally to opioids will often develop a collection of withdrawal signs
known as neonatal abstinence syndrome (NAS). The incidence of NAS has substantially …

Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior

JB Alipio, C Haga, ME Fox, K Arakawa… - Journal of …, 2021 - Soc Neuroscience
One consequence of the opioid epidemic are lasting neurodevelopmental sequelae
afflicting adolescents exposed to opioids in the womb. A translationally relevant and …

Association between prenatal opioid exposure, neonatal opioid withdrawal syndrome, and neurodevelopmental and behavioral outcomes at 5–8 months of age

LN Bakhireva, BD Holbrook, S Shrestha, Y Leyva… - Early human …, 2019 - Elsevier
Background While use of prescription opioids and medication assisted therapy (MAT) for
opioid use disorder in pregnancy, as well as the incidence of neonatal opioid withdrawal …

Neonatal abstinence syndrome: review of epidemiology, care models, and current understanding of outcomes

KDL MacMillan - Clinics in perinatology, 2019 - perinatology.theclinics.com
Background Neonatal abstinence syndrome (NAS) includes an array of symptoms impacting
opioid-exposed newborns (OEN) owing to postnatal withdrawal from in utero substance …