Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal
chemistry. Among all of the heterocyclic scaffolds, 1, 4-Dihydropyridine (1, 4-DHP) is one of …

Calcium antagonists are effective in hypertensive patients of all ethnic groups, irrespective of
age, dietary salt intake, salt-sensitivity status or plasma renin activity profile. Some …

The aim of this study was to develop and optimize SNEDDS formulations containing
surfactants reported to be bioenhancers for improvement of dissolution and oral absorption …

The purpose of the present study was to develop and optimize the microemulsion based
transdermal therapeutic system for lacidipine (LCDP), a poorly water soluble and low …

The aim of the present research work is to formulate lacidipine (LAC) loaded niosomes
formulation for the management of hypertension by thin film hydration technique. The …

Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and
causes severe hemorrhagic fever in humans. At present, there are no Food and Drug …

Context: Proniosomes offer a versatile vesicle drug delivery concept with potential for
delivery of drugs via transdermal route. Objectives: To develop proniosomal gel using …

The present study aimed to increase the in vitro dissolution rate of lacidipine, a poorly water-
soluble drug, by formulating amorphous solid dispersions (ASDs) using hot-melt extrusion …

The COVID-19 pandemic has reached over 100 million worldwide. Due to the multi-targeted
nature of the virus, it is clear that drugs providing anti-COVID-19 effects need to be …

After decades of being considered non-pathogenic, Zika virus (ZIKV) emerged as an
important threat to human health during the epidemic of 2015–2016. ZIKV infections are …