Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …

The functions of, and interactions between, the innate and adaptive immune systems are
vital for anticancer immunity. Cytotoxic T cells expressing cell-surface CD8 are the most …

Clinical immunotherapy of solid tumors elicits durable responses only in a minority of
patients, largely due to the highly immunosuppressive tumor microenvironment (TME) …

Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality,
underscores the urgent need for enhanced insights into the molecular and cellular …

Malignant transformation is characterized by dysregulation of diverse cellular processes that
have been the subject of detailed genetic, biochemical, and structural studies, but only …

High-fidelity DNA replication is critical for the faithful transmission of genetic information to
daughter cells. Following genotoxic stress, specialized DNA damage tolerance pathways …

The cardinal stages of macroautophagy are driven by core autophagy‐related (ATG)
proteins, whose ablation largely abolishes intracellular turnover. Disrupting ATG genes is …

As an emerging new class, metal nanoparticles and especially silver nanoparticles hold
great potential in the field of cancer biology. Due to cancer-specific targeting, the …

Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …