[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up
MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …
opportunities for biomedical research. Although several PLGA-based systems have already …
Modernizing pharmaceutical manufacturing: from batch to continuous production
SL Lee, TF O'Connor, X Yang, CN Cruz… - Journal of …, 2015 - Springer
Abstract The Food and Drug Administration (FDA) regulates pharmaceutical drug products
to ensure a continuous supply of high-quality drugs in the USA. Continuous processing has …
to ensure a continuous supply of high-quality drugs in the USA. Continuous processing has …
[HTML][HTML] The future of pharmaceutical manufacturing sciences
J Rantanen, J Khinast - Journal of pharmaceutical sciences, 2015 - Elsevier
The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …
solutions and fundamental scientific work, enabling the production of highly engineered …
[HTML][HTML] Recent developments in the crystallization process: toward the pharmaceutical industry
Crystallization is one of the oldest separation and purification unit operations, and has
recently contributed to significant improvements in producing higher-value products with …
recently contributed to significant improvements in producing higher-value products with …
[HTML][HTML] Progress of pharmaceutical continuous crystallization
D Zhang, S Xu, S Du, J Wang, J Gong - Engineering, 2017 - Elsevier
Crystallization is an important unit operation in the pharmaceutical industry. At present, most
pharmaceutical crystallization processes are performed in batches. However, due to product …
pharmaceutical crystallization processes are performed in batches. However, due to product …
Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization
T McGlone, NEB Briggs, CA Clark… - … Process Research & …, 2015 - ACS Publications
Continuous crystallization is an attractive approach for the delivery of consistent particles
with specified critical quality attributes (CQAs), which are attracting increased interest for the …
with specified critical quality attributes (CQAs), which are attracting increased interest for the …
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence… - Annual review of …, 2018 - annualreviews.org
The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …
processing for the manufacture of new therapies currently in development. The …
Recent progress in continuous manufacturing of oral solid dosage forms
V Vanhoorne, C Vervaet - International Journal of Pharmaceutics, 2020 - Elsevier
Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …
industry. Although the benefits related to the quality and cost of continuous manufacturing …
Designs of continuous-flow pharmaceutical crystallizers: developments and practice
Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …
pharmaceuticals and fine chemicals. This review describes recent advances in research on …
Achieving continuous manufacturing: Technologies and approaches for synthesis, workup, and isolation of drug substance. May 20–21, 2014 Continuous …
IR Baxendale, RD Braatz, BK Hodnett… - Journal of …, 2015 - Wiley Online Library
This whitepaper highlights current challenges and opportunities associated with continuous
synthesis, workup, and crystallization of active pharmaceutical ingredients (drug …
synthesis, workup, and crystallization of active pharmaceutical ingredients (drug …