The spectrum of cognitive decline in the elderly ranges from what can be classified as
normal cognitive decline with aging to subjective cognitive impairment to mild cognitive …

Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

Background Neuroimaging studies help us better understand the pathophysiology and
symptoms of Parkinson's disease (PD). In several of these studies, diffusion tensor imaging …

Abstract Introduction In PD, Mild Cognitive Impairment (PD-MCI) occurs since early stages of
disease. The aims were to assess presence of PD-MCI in untreated, drug-naive PD patients …

Background Poor quality of life (QoL) is a feature of people with Parkinson's disease (PD)
who develop dementia. The relationship between mild cognitive impairment in PD (PD-MCI) …

Objective Mild cognitive impairment in Parkinson's disease (PD‐MCI) has been suggested
to be a predictor for the development of PD dementia (PDD). This study explored the …

The use of the emerging “omics” technologies for large scale population screening is
promising in terms of predictive, preventive and personalized medicine. For Parkinson's …

The search for diagnostic and prognostic biomarkers for neurodegenerative conditions is of
high importance, since these disorders may present difficulties in differential diagnosis …

Parkinson's disease (PD) is a neurodegenerative disorder resulting from degeneration of the
substantia nigra and the dopaminergic nigrostriatal pathway. Most treatments are geared …

Mobility deficits, including gait disturbance, balance impairments and falls, are common
features of Parkinson's disease (PD) that negatively impact quality of life. Mobility deficits …