Biology of colorectal liver metastases: a review

NC Bird, D Mangnall, AW Majeed - Journal of surgical oncology, 2006 - Wiley Online Library
Metastatic growth is a selective, non‐random process, which in the case of colorectal
cancer, frequently occurs in the liver and is the major cause of cancer related death in these …

Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis

S Gout, PL Tremblay, J Huot - Clinical & experimental metastasis, 2008 - Springer
Metastatic spreading is a dreadful complication of neoplastic diseases that is responsible for
most deaths due to cancer. It consists in the formation of secondary neoplasms from cancer …

[HTML][HTML] MDA-MB-435 human breast carcinoma cell homo-and heterotypic adhesion under flow conditions is mediated in part by Thomsen-Friedenreich antigen …

SK Khaldoyanidi, VV Glinsky, L Sikora… - Journal of Biological …, 2003 - ASBMB
The importance of Thomsen-Friedenreich antigen (T antigen)-galectin-3 interactions in
adhesion of human breast carcinoma cells to the endothelium under conditions of flow was …

Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases

PL Tremblay, FA Auger, J Huot - Oncogene, 2006 - nature.com
The invasive properties of cancer cells depend on their intrinsic motile potential and on their
ability to breach the endothelial barrier. In the present work, we investigated the …

Proton pump inhibitors and histamine 2 blockers are associated with improved overall survival in patients with head and neck squamous carcinoma

S Papagerakis, E Bellile, LA Peterson, M Pliakas… - Cancer Prevention …, 2014 - AACR
It has been postulated that gastroesophageal reflux plays a role in the etiology of head and
neck squamous cell carcinomas (HNSCC) and contributes to complications after surgery or …

[HTML][HTML] Natural history of hepatic metastases from colorectal cancer-pathobiological pathways with clinical significance

KA Paschos, AW Majeed, NC Bird - World Journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer hepatic metastases represent the final stage of a multi-step biological
process. This process starts with a series of mutations in colonic epithelial cells, continues …

Role of tumor cell adhesion and migration in organ-specific metastasis formation

P Gassmann, A Enns, J Haier - Oncology Research and Treatment, 2004 - karger.com
To form clinically evident metastases-the main cause of death in cancer patients-, tumor
cells (TC) must complete a highly complex series of steps called the metastatic cascade …

Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling

V Thamilselvan, MD Basson - Gastroenterology, 2004 - Elsevier
Background & Aims: Few circulating tumor cells implant or cause metastasis. We
hypothesized that venous or lymphatic pressure or iatrogenic pressure during resection …

The utility of FDG-PET/CT as an effective tool for detecting recurrent colorectal cancer regardless of serum CEA levels

Y Sanli, S Kuyumcu, ZG Ozkan, L Kilic, E Balik… - Annals of nuclear …, 2012 - Springer
Purpose Tumor recurrence of colorectal cancers (CRC) is generally followed up by analyses
of the serum carcinoembryonic antigen (CEA) levels. However, recent evidence suggests …

Cell exfoliation in the human colon: myth, reality and implications for colorectal cancer screening

A Loktionov - International journal of cancer, 2007 - Wiley Online Library
Colonocyte exfoliation in the human colon constitutes a unique mechanism of cell
population control that can undergo significant changes under different physiological and …