Perspectives on the development and future of oocyte IVM in clinical practice
Oocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain
mature oocytes following culture of immature cumulus–oocyte complexes collected from …
mature oocytes following culture of immature cumulus–oocyte complexes collected from …
[HTML][HTML] Future potential of in vitro maturation including fertility preservation
J Cadenas, L la Cour Poulsen, LS Mamsen… - Fertility and …, 2023 - Elsevier
In several mammalian species, oocytes from small antral follicles after in vitro maturation
(IVM) are successfully used for procreation. Humans are the exception, mainly because of …
(IVM) are successfully used for procreation. Humans are the exception, mainly because of …
Intrafollicular concentrations of the oocyte-secreted factors GDF9 and BMP15 vary inversely in polycystic ovaries
SG Kristensen, A Kumar, LS Mamsen… - The Journal of …, 2022 - academic.oup.com
Context The oocyte-secreted factors growth differentiation factor 9 (GDF9) and bone
morphogenetic protein 15 (BMP15) play essential roles in follicle development and oocyte …
morphogenetic protein 15 (BMP15) play essential roles in follicle development and oocyte …
Polymorphism Detection of GDF9 Gene and Its Association with Litter Size in Luzhong Mutton Sheep (Ovis aries)
F Wang, M Chu, L Pan, X Wang, X He, R Zhang, L Tao… - Animals, 2021 - mdpi.com
Simple Summary GDF9 and BMPR1B are two important reproduction genes. In this study,
the whole coding region of GDF9 was sequenced, of which the mutations were detected in …
the whole coding region of GDF9 was sequenced, of which the mutations were detected in …
In vitro maturation without gonadotropins versus in vitro fertilization with hyperstimulation in women with polycystic ovary syndrome: a non-inferiority randomized …
X Zheng, W Guo, L Zeng, D Zheng, S Yang… - Human …, 2022 - academic.oup.com
STUDY QUESTION Does in vitro maturation (IVM) result in non-inferior cumulative live birth
rates compared to those after standard in vitro fertilization (IVF) in infertile women with …
rates compared to those after standard in vitro fertilization (IVF) in infertile women with …
Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM
J Cadenas, SE Pors, A Kumar, B Kalra… - Reproductive Biology …, 2022 - Springer
Background The suggested effects of the oocyte secreted GDF9 and BMP15 growth factors
on oocyte maturation are currently based on recombinant proteins, and little is known about …
on oocyte maturation are currently based on recombinant proteins, and little is known about …
Phycocyanin improves reproductive ability in obese female mice by restoring ovary and oocyte quality
X Wen, Z Han, SJ Liu, X Hao, XJ Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Reproductive dysfunction associated with obesity is increasing among women of
childbearing age. Emerging evidence indicates that maternal obesity impairs embryo …
childbearing age. Emerging evidence indicates that maternal obesity impairs embryo …
Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM
Purpose In vitro maturation (IVM) is a technology that generates mature oocytes following
culture of immature cumulus-oocyte complexes (COC) in vitro. IVM is characterized by …
culture of immature cumulus-oocyte complexes (COC) in vitro. IVM is characterized by …
[HTML][HTML] Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency-a systematic …
The leading indicator for successful outcomes in in-vitro fertilization (IVF) is the quality of
gametes in oocytes and sperm. Thus, advanced research aims to highlight the parameter in …
gametes in oocytes and sperm. Thus, advanced research aims to highlight the parameter in …
A rare germline BMP15 missense mutation causes hereditary ovarian immature teratoma in human
Y Liu, H Fan, X Kang, Y Hao, N Wang… - Proceedings of the …, 2024 - National Acad Sciences
Ovarian immature teratomas (OITs) are malignant tumors originating from the ovarian germ
cells that mainly occur during the first 30 y of a female's life. Early age of onset strongly …
cells that mainly occur during the first 30 y of a female's life. Early age of onset strongly …