Atherosclerotic cardio-cerebrovascular disease and death remain the leading cause of
morbidity and mortality worldwide. Defective efferocytosis, the clearance of apoptotic cells by …

Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

Atherosclerosis is commonly looked upon as a chronic inflammatory disease of the arterial
wall arising from an unbalanced lipid metabolism and a maladaptive inflammatory response …

Macrophages represent a major immune cell population in atherosclerotic plaques and play
central role in the progression of this lipid-driven chronic inflammatory disease. Targeting …

Aims Mental stress substantially contributes to the initiation and progression of human
disease, including cardiovascular conditions. We aim to investigate the underlying …

Atherosclerosis is the main pathophysiological process underlying coronary artery disease
(CAD). Acute complications of atherosclerosis, such as myocardial infarction, are caused by …

Effective immune responses require the directed migration of leukocytes from the
vasculature to the site of injury or infection. How immune cells “find” their site of …

Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, and its main complications—myocardial infarction and ischemic stroke …

Myocardial infarction (MI) leads to a systemic surge of vascular inflammation in mice and
humans, resulting in secondary ischemic complications and high mortality. We show that, in …

Infiltration of leukocyte subsets is a driving force of atherosclerotic lesion growth, and during
the past decade, neutrophils have received growing attention in chronic inflammatory …