Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics

MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …

Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis

F Montecucco, F Mach - Rheumatology, 2009 - academic.oup.com
RA is characterized by a systemic inflammatory state, in which immune cells and soluble
mediators play a crucial role. These inflammatory processes resemble those in other chronic …

The risk of pulmonary embolism and deep vein thrombosis in rheumatoid arthritis: a UK population-based outpatient cohort study

HK Choi, YH Rho, Y Zhu, L Cea-Soriano… - Annals of the …, 2013 - ard.bmj.com
Background Recent hospital-based studies have suggested a sixfold increased risk of
pulmonary embolism (PE) in rheumatoid arthritis (RA) in the year following admission. We …

The risk and trend of pulmonary embolism and deep vein thrombosis in rheumatoid arthritis: a general population-based study

L Li, N Lu, AM Avina-Galindo, Y Zheng… - …, 2021 - academic.oup.com
Objectives To estimate the overall risk of venous thromboembolism (VTE), pulmonary
embolism (PE) and deep vein thrombosis (DVT) among patients newly diagnosed with RA …

Positive antiphospholipid antibodies: observation or treatment?

B Grygiel-Górniak, Ł Mazurkiewicz - Journal of thrombosis and …, 2023 - Springer
Antiphospholipid antibodies (APLAs) are primarily directed toward phospholipid-binding
proteins and are responsible for thrombotic events. APLAs include anti-β2Glycoprotein I …

Noncardiac vascular disease in rheumatoid arthritis: increase in venous thromboembolic events?

AK Bacani, SE Gabriel, CS Crowson… - Arthritis & …, 2012 - Wiley Online Library
Objective To investigate the incidence of noncardiac vascular disease in a community‐
based incidence cohort of patients with rheumatoid arthritis (RA) and compare it to that in the …

Risk of venous thromboembolism with janus kinase inhibitors in inflammatory immune diseases: a systematic review and meta-analysis

J Zhang, W Li, M Gong, Y Gu, H Zhang… - Frontiers in …, 2023 - frontiersin.org
Objectives: This study aimed to evaluate the risk of venous thrombosis (VTE) associated with
Janus kinase (JAK) inhibitors in patients diagnosed with immune-mediated inflammatory …

Epidemiology of antiphospholipid syndrome in Korea: a nationwide population-based study

JJ Hwang, SH Shin, YJ Kim, YM Oh… - Journal of Korean …, 2020 - synapse.koreamed.org
Background Antiphospholipid syndrome (APS) is a systemic autoimmune disorder
characterized by arterial and venous thrombosis or pregnancy morbidity in patients with …

Cardiovascular disease in rheumatoid arthritis: risk factors, autoantibodies, and the effect of antirheumatic therapies

MS Fazeli, V Khaychuk, K Wittstock… - Clinical Medicine …, 2021 - journals.sagepub.com
Objective: To scope the current published evidence on cardiovascular risk factors in
rheumatoid arthritis (RA) focusing on the role of autoantibodies and the effect of …

Antiphospholipid antibodies in inflammatory and autoimmune rheumatic and musculoskeletal diseases beyond lupus: a systematic review of the available evidence

G El Hasbani, M Viola, S Sciascia, AT Taher… - Rheumatology and …, 2021 - Springer
Background The diagnosis of antiphospholipid syndrome (APS) requires the presence of
thrombosis and/or recurrent miscarriages along with one or more anti-phospholipid …