[HTML][HTML] Circular RNAs as competing endogenous RNAs in cardiovascular and cerebrovascular diseases: molecular mechanisms and clinical implications

X Min, D Liu, X Xiong - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Circular RNAs (circRNAs) represent a novel class of widespread and diverse endogenous
RNA molecules. This unusual class of RNA species is generated by a back-splicing event of …

Circular RNA expression: Its potential regulation and function in abdominal aortic aneurysms

Y Han, H Zhang, C Bian, C Chen, S Tu… - Oxidative medicine …, 2021 - Wiley Online Library
Abdominal aortic aneurysms (AAAs) have posed a great threat to human life, and the
necessity of its monitoring and treatment is decided by symptomatology and/or the aneurysm …

Circular RNA circCHFR downregulation protects against oxidized low-density lipoprotein-induced endothelial injury via regulation of microRNA-15b-5p/growth arrest …

Y Li, B Wang - Bioengineered, 2022 - Taylor & Francis
Atherosclerosis is the leading cause of coronary heart disease. In recent years,
circ_0029589 (circCHFR) has been found to be associated with atherosclerosis …

[HTML][HTML] circDENND1B participates in the antiatherosclerotic effect of IL-1β monoclonal antibody in mouse by promoting cholesterol efflux via miR-17-5p/Abca1 axis

F Xu, L Shen, H Chen, R Wang, T Zang… - Frontiers in Cell and …, 2021 - frontiersin.org
Inflammation is a crucial mediator of atherosclerosis, and several therapeutic methods that
focus on inflammatory cytokines, including interleukin-1β (IL-1β), have proven effective in …

Insights into circular RNAs: Biogenesis, function and their regulatory roles in cardiovascular disease

C Ding, Y Zhou - Journal of Cellular and Molecular Medicine, 2023 - Wiley Online Library
As a distinctive member of the noncoding RNA family, circular RNAs (circRNAs) are
generated from single‐stranded, covalently closed structures and are ubiquitous in …

Circular RNA hsa_circ_0008896 accelerates atherosclerosis by promoting the proliferation, migration and invasion of vascular smooth muscle cells via hsa-miR-633 …

X Hou, H Dai, Y Zheng - Bioengineered, 2022 - Taylor & Francis
Circular RNAs, a class of circularly closed non-coding RNAs, play essential roles in the
formation of atherosclerosis, which is a frequent cause of cardiovascular and …

Circ_GRN promotes the proliferation, migration, and inflammation of vascular smooth muscle cells in atherosclerosis through miR-214-3p/FOXO1 axis

X Li, L Li, X Dong, J Ding, H Ma… - Journal of Cardiovascular …, 2021 - journals.lww.com
Dysfunction of vascular smooth muscle cells (VSMCs) assumes a fundamental part in the
pathogenesis of atherosclerosis (AS). Circular RNA granulin precursor (circ_GRN) was …

Circ-USP9X Inhibition Reduces Oxidized Low-density Lipoprotein–induced Endothelial Cell Injury via the microRNA 599/Chloride Intracellular Channel 4 Axis

H Peng, J Sun, Y Li, Y Zhang… - Journal of Cardiovascular …, 2021 - journals.lww.com
Atherosclerosis (AS) is the common pathological basis of cardiovascular disease. Circular
RNA circ-USP9X (hsa_circ_0090231) has been discovered to be upregulated in oxidized …

[HTML][HTML] Emerging Roles of extracellular vesicle-delivered circular RNAs in atherosclerosis

C Wen, B Li, L Nie, L Mao, Y Xia - Frontiers in Cell and …, 2022 - frontiersin.org
Atherosclerosis (AS) is universally defined as chronic vascular inflammation induced by
dyslipidaemia, obesity, hypertension, diabetes and other risk factors. Extracellular vesicles …

Circular RNA circ_0029589 promotes ox-LDL-induced endothelial cell injury through regulating RAB22A by serving as a sponge of miR-1197

D He, Z Li, Y Chen, M Huang - Clinical Hemorheology and …, 2023 - content.iospress.com
BACKGROUND: Dysfunction of endothelial cells is now considered a vital contributor to the
pathogenesis of atherosclerosis (AS). Moreover, circular RNA (circRNA) circ_0029589 has …