Treatment-related adverse events of PD-1 and PD-L1 inhibitors in clinical trials: a systematic review and meta-analysis

Y Wang, S Zhou, F Yang, X Qi, X Wang, X Guan… - JAMA …, 2019 - jamanetwork.com
Importance Programmed cell death (PD-1) and programmed cell death ligand 1 (PD-L1)
inhibitors have been increasingly used in cancer therapy. Understanding the treatment …

Response efficacy of PD-1 and PD-L1 inhibitors in clinical trials: a systematic review and meta-analysis

S Chen, Z Zhang, X Zheng, H Tao, S Zhang… - Frontiers in …, 2021 - frontiersin.org
Background Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have
demonstrated promise in treating a variety of advanced cancers; however, little is known …

Efficacy of PD-1/PD-L1 blockade monotherapy in clinical trials

B Zhao, H Zhao, J Zhao - Therapeutic advances in medical …, 2020 - journals.sagepub.com
Background: Inhibitors targeting programmed cell death 1 (PD-1) and programmed death-
ligand 1 (PD-L1) have unprecedented effects in cancer treatment. However, the objective …

Immune checkpoint inhibitor associated hepatotoxicity in primary liver cancer versus other cancers: a systematic review and meta‐analysis

J Fu, WZ Li, NA McGrath, CW Lai, G Brar… - Frontiers in …, 2021 - frontiersin.org
Background Overall risks of hepatotoxicity with immune checkpoint inhibitors (ICIs) have yet
to be compared in primary liver cancers to other solid tumors. Methods We reviewed data …

miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox …

H Du, Y Bao, C Liu, A Zhong… - Molecular Medicine …, 2021 - spandidos-publications.com
The development of chemotherapeutic dug resistance hinders the clinical treatment of
cancer. MicroRNAs (miRNAs/miRs) have been revealed to serve essential roles in the drug …

Incidence of Cutaneous Immune-Related Adverse Events and Outcomes in Immune Checkpoint Inhibitor-Containing Regimens: A Systematic Review and Meta …

NB Curkovic, K Bai, F Ye, DB Johnson - Cancers, 2024 - mdpi.com
Simple Summary Immune checkpoint inhibitors are increasingly being used in the treatment
of a variety of cancers, both alone and in combination with other cancer therapies. Side …

Vascular events with immune checkpoint inhibitors in melanoma or non-small cell lung cancer: A systematic review and meta-analysis

M Giustozzi, C Becattini, F Roila, G Agnelli… - Cancer Treatment …, 2021 - Elsevier
The incidence of venous and arterial thromboembolic events in advanced cancer patients
treated with immune checkpoint inhibitors (ICIs) has been sporadically reported. We …

[HTML][HTML] Immune-checkpoint inhibitors as the first line treatment of advanced non-small cell lung cancer: a meta-analysis of randomized controlled trials

Y Chen, Y Zhou, L Tang, X Peng, H Jiang… - Journal of …, 2019 - ncbi.nlm.nih.gov
Background: This meta-analysis aimed to explore if immunotherapy or chemotherapy alone
or in combination is a better first line treatment strategy for advanced non-small cell lung …

Treatment-related serious adverse events of immune checkpoint inhibitors in clinical trials: a systematic review

T Ouyang, Y Cao, X Kan, L Chen, Y Ren, T Sun… - Frontiers in …, 2021 - frontiersin.org
Background Immune Checkpoint Inhibitors (ICI) have been progressively used in cancer
treatment and produced unique toxicity profiles. This systematic review aims to comprehend …

[HTML][HTML] Are there any ethnic differences in the efficacy and safety of immune checkpoint inhibitors for treatment of lung cancer?

J Lee, JM Sun, SH Lee, JS Ahn, K Park… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
Immunotherapy, especially immune checkpoint inhibitors, has revolutionized the treatment
of non-small cell lung cancer. However, data on ethnic differences in response to these …