Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion
Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve
(CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration …
(CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration …
European Society for Sexual Medicine consensus statement on the use of the cavernous nerve injury rodent model to study postradical prostatectomy erectile …
Introduction Rodent animal models are currently the most used in vivo model in translational
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …
Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve …
I Kovanecz, S Rivera, G Nolazco… - The journal of sexual …, 2012 - academic.oup.com
Introduction Long-term daily administration of phosphodiesterase type 5 (PDE5) inhibitors in
the rat prevents or reverses corporal veno-occlusive dysfunction (CVOD) and smooth …
the rat prevents or reverses corporal veno-occlusive dysfunction (CVOD) and smooth …
Drug delivery options and therapeutic advances in the management of erectile dysfunction
PT Grice, J Liu, AT Gabrielson, I Pearce… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Erectile dysfunction (ED) is defined as the inability to achieve or maintain an
erection sufficient for satisfactory sexual performance. It is estimated that 20–30% of adult …
erection sufficient for satisfactory sexual performance. It is estimated that 20–30% of adult …
Emerging tools for erectile dysfunction: a role for regenerative medicine
L Hakim, F Van der Aa, TJ Bivalacqua… - Nature Reviews …, 2012 - nature.com
Erectile dysfunction (ED) is the most common sexual disorder reported by men to their
health-care providers and the most investigated male sexual dysfunction. Currently, the …
health-care providers and the most investigated male sexual dysfunction. Currently, the …
Nanotechnology-assisted adipose-derived stem cell (ADSC) therapy for erectile dysfunction of cavernous nerve injury: in vivo: cell tracking, optimized injection dosage …
H Wu, WH Tang, LM Zhao, DF Liu… - Asian journal of …, 2018 - journals.lww.com
Stem cell therapy is a potentially promising option for erectile dysfunction; however, its risk of
tumorigenicity is a clinical hurdle and the risk is positively related to the number of injected …
tumorigenicity is a clinical hurdle and the risk is positively related to the number of injected …
Stem-cell therapy for erectile dysfunction
R Yiou - Bio-medical materials and engineering, 2017 - content.iospress.com
Stem cell-based therapies have been recently investigated in the field of organic erectile
dysfunctions, such as those associated with diabetes or the treatment of prostate cancer …
dysfunctions, such as those associated with diabetes or the treatment of prostate cancer …
Beneficial effect of PEDF-transfected ADSCs on erectile dysfunction in a streptozotocin-diabetic rat model
J Lu, Z Xin, Q Zhang, D Cui, Y Xiao, J Zhuo, F Sun… - Cell and tissue …, 2016 - Springer
Diabetes mellitus (DM) is an important risk factor for erectile dysfunction. Adipose-derived
stem cells (ADSCs) are essential for maintaining erectile function but their function is …
stem cells (ADSCs) are essential for maintaining erectile function but their function is …
Intratunical injection of stromal vascular fraction prevents fibrosis in a rat model of Peyronie's disease
F Castiglione, P Hedlund, E Weyne, L Hakim… - BJU …, 2019 - Wiley Online Library
Objective To investigate whether local injection of autologous adipose stromal vascular
fraction (SVF) can prevent the development of fibrosis and elastosis in the tunica albuginea …
fraction (SVF) can prevent the development of fibrosis and elastosis in the tunica albuginea …
Regeneration of sensory but not motor axons following visceral nerve injury
SC Payne, PJ Belleville, JR Keast - Experimental neurology, 2015 - Elsevier
Following peripheral nerve injury, restoration of function may occur via the regeneration of
injured axons or compensatory sprouting of spared axons. Injury to visceral nerves that …
injured axons or compensatory sprouting of spared axons. Injury to visceral nerves that …