Sleep—A brain-state serving systems memory consolidation
Although long-term memory consolidation is supported by sleep, it is unclear how it differs
from that during wakefulness. Our review, focusing on recent advances in the field, identifies …
from that during wakefulness. Our review, focusing on recent advances in the field, identifies …
Memory engrams: Recalling the past and imagining the future
SA Josselyn, S Tonegawa - Science, 2020 - science.org
BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory
A Guskjolen, MS Cembrowski - Molecular psychiatry, 2023 - nature.com
Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …
Navigating for reward
M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …
associated with rewards, such as food or a home. Accumulating research has revealed that …
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice
Executing memory-guided behavior requires storage of information about experience and
later recall of that information to inform choices. Awake hippocampal replay, when …
later recall of that information to inform choices. Awake hippocampal replay, when …
Bidirectional prefrontal-hippocampal dynamics organize information transfer during sleep in humans
How are memories transferred from short-term to long-term storage? Systems-level memory
consolidation is thought to be dependent on the coordinated interplay of cortical slow waves …
consolidation is thought to be dependent on the coordinated interplay of cortical slow waves …
Constant sub-second cycling between representations of possible futures in the hippocampus
Cognitive faculties such as imagination, planning, and decision-making entail the ability to
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …
represent hypothetical experience. Crucially, animal behavior in natural settings implies that …
Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes
Sleep is thought to support memory consolidation via reactivation of prior experiences, with
particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) …
particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) …
[HTML][HTML] Neuronal computation underlying inferential reasoning in humans and mice
Every day we make decisions critical for adaptation and survival. We repeat actions with
known consequences. But we also draw on loosely related events to infer and imagine the …
known consequences. But we also draw on loosely related events to infer and imagine the …
Memory consolidation as an adaptive process
We rely on our long-term memories to guide future behaviors, making it adaptive to prioritize
the retention of goal-relevant, salient information in memory. In this review, we discuss …
the retention of goal-relevant, salient information in memory. In this review, we discuss …