Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

The function of the hepatitis B e antigen (HBeAg) is largely unknown because it is not
required for viral assembly, replication, or infection. In this report we chronicle clinical and …

The core (capsid) protein of hepatitis B virus (HBV) is the building block of nucleocapsids
where viral DNA reverse transcriptional replication takes place and mediates virus-host cell …

The hepatitis B (HBV) 1 and C (HCV) viruses are noncytopathic, hepatotropic viruses that
cause acute and chronic hepatitis and hepatocellular carcinoma (1). The cellular immune …

The capsids of most spherical viruses are icosahedral, an arrangement of multiples of 60
subunits. Though it is a salient point in the life cycle of any virus, the physical chemistry of …

A unique characteristic of the hepatitis B virus is the production of a secreted form (precore
or HBeAg) of the structural nucleocapsid (core or HBcAg). By using T cell receptor (TCR) …

The host-virus interactions that determine the outcome of viral infections have fascinated me
ever since medical school. My first opportunity to actively pursue this interest came when I …

The function of the hepatitis B virus (HBV) precore or HBeAg is largely unknown because it
is not required for viral assembly, infection, or replication. However, the HBeAg does appear …

BACKGROUND & AIMS: Viruses target innate immune pathways to evade host antiviral
responses. Recent studies demonstrate a relationship between hepatitis B disease states …

Publisher Summary Although most living biological systems have developed intricate
mechanisms to keep the genetic information stable, many viruses, including hepatitis B virus …