Background: Gastric and colorectal carcinomas are associated with increased mortality and
an increasing incidence worldwide, while surgical resection remains the primary approach …

Abstract Delta-5 desaturase (D5D) is a rate-limiting enzyme that introduces double-bonds to
the delta-5 position of the n-3 and n-6 polyunsaturated fatty acid chain. Since fatty acid …

Background This study aimed to evaluate the clinical significance of pre-treatment Naples
prognostic score (NPS) in patients with osteosarcoma. Methods The clinical data of 133 …

Objective Emerging studies highlight the crucial effects of microRNAs on cancer initiation
and malignant progression of various tumors. This study focused on the biological effect of …

Background: Geiparvarin (GN) is a natural compound isolated from the leaves of Geijera
parviflora and exhibits anticancer activity. Nevertheless, little is known about its anticancer …

Objective To investigate the biological role of miR-143 and miR-199a in mediating the
progression of osteosarcoma (OS) by targeting cyclooxygenase (COX-2). Introduction COX …

骨肉瘤是间叶组织起源的原发性骨恶性肿瘤, 主要发生于儿童和青少年, 具有恶性程度高,
生长迅速, 早期转移, 预后较差等特点. 当前, 国内外的研究方向均主要集中在治疗上 …

Autotaxin (ATX) is a secreted enzyme responsible for producing lysophosphatidic acid
(LPA). The ATX/LPA signaling axis is typically activated in wound healing and tissue repair …

The use of cryoablation/cryosurgery in treating solid tumors has been proven as a unique
technique that uses lethal temperatures to destroy the tumors and impart better functions for …

Simple Summary Pazopanib treatment in advanced solitary fibrous tumour patients,
assessed in the prospective GEIS-32 phase II clinical trial, has shown longer progression …