Cellular senescence, classically defined as stable cell cycle arrest, is implicated in biological
processes such as embryogenesis, wound healing and ageing. Senescent cells have a …

Cardiovascular disease is the leading cause of death and has dramatically increased in
recent years. Continuous cardiac monitoring is particularly important for early diagnosis and …

Naturally occurring stem cells isolated from humans have been used therapeutically for
decades. This has primarily involved the transplantation of primary cells such as …

Background: Human engineered heart tissue (EHT) transplantation represents a potential
regenerative strategy for patients with heart failure and has been successful in preclinical …

The secretome is defined as the set of molecules and biological factors that are secreted by
cells into the extracellular space. In the past decade, secretome-based therapies have …

Stem cell-derived extracellular vesicles (EVs) have been demonstrated to be effective in
heart repair and regeneration post infarction. However, the poor homing efficiency and low …

Mesenchymal stromal cell (MSC)-derived exosomes play a promising role in regenerative
medicine. Their trophic and immunomodulatory potential has made them a promising …

Abstract Platelet‐rich plasma (PRP), due to its promising therapeutic properties, has been
used in regenerative medicine for more than 30 years and numerous encouraging outcomes …

Stem cell-derived sheet engineering has been developed as the next-generation treatment
for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem …

Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …