Astrocytes comprise half of the cells in the central nervous system and play a critical role in
maintaining metabolic homeostasis. Metabolic dysfunction in astrocytes has been indicated …

Post-stroke depression (PSD) is a frequent and disabling complication of stroke that affects
up to one-third of stroke survivors. The pathophysiology of PSD involves multiple …

KCNQs are voltage-gated K+ channels that control neuronal excitability and are mutated in
epilepsy and autism spectrum disorder (ASD). KCNQs have been extensively studied in …

Phasic (fast) and tonic (sustained) inhibition of γ-aminobutyric acid (GABA) are fundamental
for regulating day-to-day activities, neuronal excitability, and plasticity. However, the …

Background and purpose Executive function impairment, a slight but noticeable cognitive
deficit in mild cognitive impairment (MCI) patients, is influenced by gamma-aminobutyric …

Postpartum depression (PPD) is a significant contributor to maternal morbidity and mortality.
The Sigma-1 (σ-1) receptor has received increasing attention in recent years because of its …

Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by
intellectual disability and is related to autism. FXS is caused by mutations of the fragile X …

Astrocytes have been in the limelight of active research for about 3 decades now. Over this
period, ideas about their function and role in the nervous system have evolved from simple …

The efficiency of neocortical information processing critically depends on the balance
between the glutamatergic (excitatory, E) and GABAergic (inhibitory, I) synaptic …

Astrocytes have an important role in neuronal maturation and synapse function in the brain.
The interplay between astrocytes and neurons is found to be altered in many …