Esophageal cancers (EC) are highly aggressive tumors, commonly presented in a locally
advanced stage with a poor prognosis and survival. Up to 50% of the patients are eligible for …

Background The mechanism of rapid growth of the residual tumor after radiofrequency (RF)
ablation is poorly understood. In this study, we investigated the effect of hyperthermia on …

Cancer stem cells (CSCs) in esophageal cancer have a key role in tumor initiation,
progression and therapy resistance. Novel therapeutic strategies to target CSCs are being …

GYY4137, a hydrogen sulfide (H2S) donor, exhibits anticancer activity by a combination of
cell cycle arrest and promoting apoptosis, and inhibits tumor growth, however, the precise …

AIM: To investigate whether hypoxia inducible factor (HIF)-1α modulates vasculogenic
mimicry (VM) by upregulating VE-cadherin expression in esophageal squamous cell …

Reactive oxygen species (ROS) play an important role in multidrug resistance (MDR). This
study aimed to investigate the effects of long‐term ROS alteration on MDR in MCF‐7 cells …

The radiotherapy outcomes of patients with advanced esophageal squamous cell carcinoma
(ESCC) remain poor due to hypoxia. Carbonic anhydrase IX (CAIX) is a membrane …

purpose. The2′, 5′-oligoadenylate-dependent RNase L gene functions in the interferon-
inducible RNA decay pathway known as the 2–5A system. The purpose of this study was to …

Background High-intensity focused ultrasound (HIFU) is a widely applied to treatment for
unresectable hepatocellular carcinoma. However, insufficient HIFU can result in rapid …

Proximal tubular cells (PTC) are particularly vulnerable to hypoxia-induced apoptosis, a
relevant factor for kidney disease. We hypothesized here that PTC death under hypoxia is …