The association between hypoxia inducible factor-1α gene polymorphisms and increased susceptibility to oral cancer
MK Chen, HL Chiou, SC Su, TT Chung, HC Tseng… - Oral oncology, 2009 - Elsevier
The aim of this study was to estimate the relations between hypoxia inducible factor-1α (HIF-
1α) gene polymorphisms, C1772T and G1790A, to the susceptibility and clinicopathological …
1α) gene polymorphisms, C1772T and G1790A, to the susceptibility and clinicopathological …
[HTML][HTML] Induction of peroxiredoxin 1 by hypoxia regulates heme oxygenase-1 via NF-κB in oral cancer
M Zhang, M Hou, L Ge, C Miao, J Zhang, X Jing… - PLoS …, 2014 - journals.plos.org
Overexpression of peroxiredoxin 1 (Prx1) has been observed in numerous cancers
including oral squamous cell carcinoma (OSCC). The precise molecular mechanism of up …
including oral squamous cell carcinoma (OSCC). The precise molecular mechanism of up …
[HTML][HTML] HIF-1α is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer
S Miyake, Y Kitajima, J Nakamura… - International …, 2013 - spandidos-publications.com
The molecular mechanisms underlying the peritoneal dissemination of gastric cancer
remain unclear. Using in vivo metastatic models, this study attempted to clarify the role of …
remain unclear. Using in vivo metastatic models, this study attempted to clarify the role of …
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells
OY Fu, MF Hou, SF Yang, SC Huang… - Anticancer …, 2009 - ar.iiarjournals.org
Background: Tumor hypoxia promotes cancer progression. Matrix metalloproteinases
(MMPs) are required for breast cancer cell invasion. Materials and Methods: The effect of …
(MMPs) are required for breast cancer cell invasion. Materials and Methods: The effect of …
Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer
DV Rozanov, AY Savinov, R Williams, K Liu… - Cancer research, 2008 - AACR
Invasion-promoting MT1-MMP is directly linked to tumorigenesis and metastasis. Our studies
led us to identify those genes, the expression of which is universally linked to MT1-MMP in …
led us to identify those genes, the expression of which is universally linked to MT1-MMP in …
[HTML][HTML] Hypoxia inducible factors modify collagen I fibers in MDA-MB-231 triple negative breast cancer xenografts
Hypoxia inducible factors (HIFs) are transcription factors that mediate the response of cells
to hypoxia. HIFs have wide-ranging effects on metabolism, the tumor microenvironment …
to hypoxia. HIFs have wide-ranging effects on metabolism, the tumor microenvironment …
Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors and transforming growth factor-β
J Strickland, D Garrison, BL Copple - Cytokine, 2020 - Elsevier
Introduction Cxcl12, or stromal-derived factor-1, is a chemokine produced by several hepatic
cell types, including hepatocytes, after liver injury and surgical resection. Studies have …
cell types, including hepatocytes, after liver injury and surgical resection. Studies have …
[HTML][HTML] Hypoxia enhances cholangiocarcinoma invasion through activation of hepatocyte growth factor receptor and the extracellular signal‑regulated kinase …
T Vanichapol, K Leelawat… - Molecular medicine …, 2015 - spandidos-publications.com
Hypoxia is associated with tumor progression and poor prognosis in several cancer types.
The present study aimed to examine the contribution of hypoxia (1% O2) to cancer …
The present study aimed to examine the contribution of hypoxia (1% O2) to cancer …
Effect of 17β-estradiol on mediators involved in mesenchymal stromal cell trafficking in cell therapy of diabetes
Background aims Mesenchymal stromal cells (MSCs) have shown great promise for cell
therapy of a wide range of diseases such as diabetes. However, insufficient viability of …
therapy of a wide range of diseases such as diabetes. However, insufficient viability of …
Coexpression of hypoxia‐inducible factor‐2α, TWIST2, and SIP1 may correlate with invasion and metastasis of salivary adenoid cystic carcinoma
C Zhou, J Liu, Y Tang, G Zhu, M Zheng… - Journal of oral …, 2012 - Wiley Online Library
J Oral Pathol Med (2012) 41: 424–431 Background: Adenoid cystic carcinoma (ACC) of
salivary gland is characterized by advanced local invasion and distant metastasis …
salivary gland is characterized by advanced local invasion and distant metastasis …