Stimuli responsive nanosonosensitizers for sonodynamic therapy

Z Jiang, W Xiao, Q Fu - Journal of Controlled Release, 2023 - Elsevier
Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors
and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth …

Dual glucose/ROS-sensitive injectable adhesive self-healing hydrogel with photothermal antibacterial activity and modulation of macrophage polarization for infected …

X Zhou, X Ning, Y Chen, H Chang, D Lu… - ACS Materials …, 2023 - ACS Publications
Antibacterial, anti-inflammatory, and healing-promoting treatment of chronically infected
wounds is not only clinical problems to be solved urgently but also important needs related …

Oxygen‐Independent Synchronized ROS Generation and Hypoxia Prodrug Activation with Z‐Scheme Heterostructure Sonosensitizer

Y Chen, T Zou, G Xin, X Liu, Y Yang, L Wei… - Advanced …, 2024 - Wiley Online Library
Combination therapy has emerged as a promising approach for effective tumor treatment.
However, the combination of sonodynamic therapy (SDT) and hypoxia‐activated prodrugs …

[HTML][HTML] Ca & Mn dual-ion hybrid nanostimulator boosting anti-tumor immunity via ferroptosis and innate immunity awakening

X Deng, T Liu, Y Zhu, J Chen, Z Song, Z Shi, H Chen - Bioactive Materials, 2024 - Elsevier
Limited by low tumor immunogenicity and the immunosuppressive tumor microenvironment
(TME), triple-negative breast cancer (TNBC) has been poorly responsive to immunotherapy …

[HTML][HTML] Responsive nanoplatforms: Versatile design strategies for efficient cancer theranostics

Y Kuang, SX Chen, H Chen - Materials & Design, 2023 - Elsevier
In recent years, with close cooperation between different disciplines, more and more smart
“all-in-one” theranostic nanoplatforms with stimulus-responsive capability have been …

In Situ Formed Microalgae-Integrated Living Hydrogel for Enhanced Tumor Starvation Therapy and Immunotherapy through Photosynthetic Oxygenation

C Zhang, ZY Han, KW Chen, YZ Wang, P Bao, P Ji… - Nano Letters, 2024 - ACS Publications
The effectiveness of various cancer therapies for solid tumors is substantially limited by the
highly hypoxic tumor microenvironment (TME). Here, a microalgae-integrated living …

“Triple-Hop” nano-bomb combining CDT, PDT and immunetherapy for NIR-triggered cancer therapy

H Chen, J Song, Y Wang, T Wang, F Zhang, Y Lv… - Chemical Engineering …, 2024 - Elsevier
The development of non-interventional combination therapy with immune activation property
provides a potential direction for solving the diversity, complexity and heterogeneity of …

[HTML][HTML] Piezo-enhanced near infrared photocatalytic nanoheterojunction integrated injectable biopolymer hydrogel for anti-osteosarcoma and osteogenesis …

C Xiao, R Wang, R Fu, P Yu, J Guo, G Li, Z Wang… - Bioactive Materials, 2024 - Elsevier
Preventing local tumor recurrence while promoting bone tissue regeneration is an urgent
need for osteosarcoma treatment. However, the therapeutic efficacy of traditional …

Injectable Responsive Hydrogel Delivery Platform: Enabling High Tissue Penetration and Sonogenetic‐Like Potentiating Anti‐Tumor Immunotherapy

Z Dai, X Li, Q Chen, Y Zhu, Z Shi… - Advanced Functional …, 2024 - Wiley Online Library
The characteristics of malignant solid tumors with dense extracellular matrix (ECM) and
immunosuppressive microenvironment (IME) seriously restrict the high efficacy and precise …

Metastructure “trap” coating by acoustic confinement effect for antibacterial sonothermal therapy

S Guan, S Chen, X Zhang, H Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Antibacterial sonothermal therapy (ASTT) is attractive for treating implant‐associated
infection, which addresses the limitations of poor penetration of photothermal therapy …