The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …

Although the pathogenesis of neurodegenerative diseases is still widely unclear, various
mechanisms have been proposed and several pieces of evidence are supportive for an …

Parkinson's disease (PD) is a complex, chronic and progressive neurodegenerative
disease. While the etiology of PD is likely multifactorial, the protein α-synuclein is a central …

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …

Mitochondria are essential organelles within the cell where most ATP is produced through
oxidative phosphorylation (OXPHOS). A subset of the genes needed for this process are …

Three-dimensional (3D) culture systems have fueled hopes to bring about the next
generation of more physiologically relevant high-throughput screens (HTS). However …

Importance Despite established genetic and pathophysiologic links between inflammatory
bowel disease (IBD) and Parkinson disease (PD), clinical data supporting this association …

Neurodegenerative diseases of the central nervous system progressively rob patients of
their memory, motor function, and ability to perform daily tasks. Advances in genetics and …

Herein, we demonstrated a strategy to regulate the conductive metal–organic framework
(MOF) surface, by the conjugated molecule wires for selective and sensitive determination of …