CHAC1 as a novel biomarker for distinguishing alopecia from other dermatological diseases and determining its severity

H Karami, S Nomiri, M Ghasemigol… - IET Systems …, 2022 - Wiley Online Library
Alopecia Areata (AA) is characterised by an autoimmune response to hair follicles (HFs) and
its exact pathobiology remains unclear. The current study aims to look into the molecular …

[HTML][HTML] Integration of gene co-expression analysis and multi-class SVM specifies the functional players involved in determining the fate of HTLV-1 infection toward the …

M Zarei Ghobadi, R Emamzadeh - Plos one, 2022 - journals.plos.org
Human T-cell Leukemia Virus type-1 (HTLV-1) is an oncovirus that may cause two main life-
threatening diseases including a cancer type named Adult T-cell Leukemia/Lymphoma …

[HTML][HTML] Identification of modules and hub genes associated with platinum-based chemotherapy resistance and treatment response in ovarian cancer by weighted …

L Zhang, X Zhang, S Fan, Z Zhang - Medicine, 2019 - journals.lww.com
High-grade serous ovarian carcinoma (HGSOC) is the most prevalent and malignant
ovarian tumor. To identify co-expression modules and hub genes correlated with platinum …

[HTML][HTML] Identifying Conserved Generic Aspergillus spp. Co-Expressed Gene Modules Associated with Germination Using Cross-Platform and Cross-Species …

TJH Baltussen, JPM Coolen, PE Verweij, J Dijksterhuis… - Journal of Fungi, 2021 - mdpi.com
Aspergillus spp. is an opportunistic human pathogen that may cause a spectrum of
pulmonary diseases. In order to establish infection, inhaled conidia must germinate …

Identification of potential prognostic markers for lung adenocarcinoma using comprehensive analysis

L Huang, A Zhang, C Tang, J Wei… - Molecular …, 2023 - spandidos-publications.com
Lung adenocarcinoma (LUAD) is a common malignancy throughout the world with high
levels of mortality and morbidity. In the present study, potential biomarkers and treatment …

[HTML][HTML] Transcriptional circuitry atlas of genetic diverse unstimulated murine and human macrophages define disparity in population-wide innate immunity

B Mishra, M Athar, MS Mukhtar - Scientific Reports, 2021 - nature.com
Macrophages are ubiquitous custodians of tissues, which play decisive role in maintaining
cellular homeostasis through regulatory immune responses. Within tissues, macrophage …

[HTML][HTML] Identify and validate RUNX2 and LAMA2 as novel prognostic signatures and correlate with immune infiltrates in bladder cancer

Y Jin, S Huang, Z Wang - Frontiers in Oncology, 2023 - frontiersin.org
Background Muscle-invasive bladder cancer (MIBC) develops lymph node (LN) metastasis
or distant metastasis, leading to recurrence and poor prognosis. The five-year survival rate …

[HTML][HTML] Gene-network based analysis of human placental trophoblast subtypes identifies critical genes as potential targets of therapeutic drugs

AI Lackner, J Pollheimer, P Latos, M Knöfler… - Journal of Integrative …, 2024 - degruyter.com
During early pregnancy, extravillous trophoblasts (EVTs) play a crucial role in modifying the
maternal uterine environment. Failures in EVT lineage formation and differentiation can lead …

[HTML][HTML] Proteome Network Analysis Identifies Potential Biomarkers for Brain Aging

MI Short, AE Fohner, HK Skjellegrind… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease and related dementias (ADRD) involve biological
processes that begin years to decades before onset of clinical symptoms. The plasma …

A network approach to identify biomarkers of differential chemotherapy response using patient-derived xenografts of triple-negative breast cancer

V Petrosyan, LE Dobrolecki, L Thistlethwaite, AN Lewis… - BioRxiv, 2021 - biorxiv.org
Triple negative breast cancer (TNBC) is a highly heterogeneous set of diseases that has,
until recently, lacked any FDA-approved, molecularly targeted therapeutics. Thus, systemic …