The genome-wide transcription profile of Escherichia coli cells treated with hydrogen
peroxide was examined with a DNA microarray composed of 4,169 E. coli open reading …

Plants are constantly confronted by multiple types of stress. Despite their distinct origin and
mode of perception, nutrient deprivation and most stresses have an impact on the overall …

A complete description of protein metabolism requires knowledge of the rates of protein
production and destruction within cells. Using an epitope-tagged strain collection, we …

Cells coordinate intracellular activities in response to changes in the extracellular
environment to maximize their probability of survival and proliferation. Eukaryotic cells need …

During brewery handling, production strains of yeast must respond to fluctuations in
dissolved oxygen concentration, pH, osmolarity, ethanol concentration, nutrient supply and …

TFIID and SAGA share a common set of TAFs, regulate chromatin, and deliver TBP to
promoters. Here we examine their relationship within the context of the Saccharomyces …

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The main focus in development of yeast cell factories has generally been on establishing
optimal activity of heterologous pathways and further metabolic engineering of the host …

The identification of nuclease-hypersensitive sites in an active globin gene and in the 5′
regions of fruit fly heat shock genes first suggested that chromatin changes accompany gene …

Histone acetyltransferases and deacetylases with specificities for different sites of
acetylation affect common chromatin regions. This could generate unique patterns of …