Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton
JR Peterson, TJ Mitchison - Chemistry & biology, 2002 - cell.com
Chemical inhibitors, whether natural products or synthetic, have had an enormous impact on
the study of the eukaryotic cytoskeleton. Here we review the history of some of the most …
the study of the eukaryotic cytoskeleton. Here we review the history of some of the most …
[PDF][PDF] Glutathione, altruistic metabolite in fungi
Glutathione, altruistic metabolite in fungi Page 2 Contents CONTRIBUTORS TO VOLUME
49 vii Glutathione, Altruistic Metabolite in Fungi Istvan Pocsi, Rolf A. Prade and Michel J …
49 vii Glutathione, Altruistic Metabolite in Fungi Istvan Pocsi, Rolf A. Prade and Michel J …
Defining the essential function of yeast Hsf1 reveals a compact transcriptional program for maintaining eukaryotic proteostasis
EJ Solís, JP Pandey, X Zheng, DX Jin, PB Gupta… - Molecular cell, 2016 - cell.com
Despite its eponymous association with the heat shock response, yeast heat shock factor 1
(Hsf1) is essential even at low temperatures. Here we show that engineered nuclear export …
(Hsf1) is essential even at low temperatures. Here we show that engineered nuclear export …
Genome-wide analysis of mRNA stability using transcription inhibitors and microarrays reveals posttranscriptional control of ribosome biogenesis factors
J Grigull, S Mnaimneh, J Pootoolal… - … and cellular biology, 2004 - Am Soc Microbiol
Using DNA microarrays, we compared global transcript stability profiles following chemical
inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase …
inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase …
Evaluation and comparison of gene clustering methods in microarray analysis
A Thalamuthu, I Mukhopadhyay, X Zheng… - …, 2006 - academic.oup.com
Motivation: Microarray technology has been widely applied in biological and clinical studies
for simultaneous monitoring of gene expression in thousands of genes. Gene clustering …
for simultaneous monitoring of gene expression in thousands of genes. Gene clustering …
The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or …
Profiles of genome-wide transcriptional events for a given environmental condition can be of
importance in the diagnosis of poorly defined environments. To identify clusters of genes …
importance in the diagnosis of poorly defined environments. To identify clusters of genes …
Adaptation of cells to new environments
The evolutionary success of an organism is a testament to its inherent capacity to keep pace
with environmental conditions that change over short and long periods. Mechanisms …
with environmental conditions that change over short and long periods. Mechanisms …
Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures
Environmental mixtures of chemicals constitute a prevalent issue in ecotoxicology and the
development of new methods to reduce the uncertainties associated with their ecological …
development of new methods to reduce the uncertainties associated with their ecological …
Specialization can drive the evolution of modularity
C Espinosa-Soto, A Wagner - PLoS computational biology, 2010 - journals.plos.org
Organismal development and many cell biological processes are organized in a modular
fashion, where regulatory molecules form groups with many interactions within a group and …
fashion, where regulatory molecules form groups with many interactions within a group and …