Cells respond to their environment by modulating protein levels through mRNA transcription
and post-transcriptional control. Modest observed correlations between global steady-state …

We compared the transcriptomes of Saccharomyces cerevisiae cells growing under steady-
state conditions on 21 unique sources of nitrogen. We found 506 genes differentially …

Superoxide dismutase (SOD) is an enzyme that converts superoxide radicals into hydrogen
peroxide and molecular oxygen and has been shown to contribute to the virulence of many …

Current methods for the functional analysis of microarray gene expression data make the
implicit assumption that genes with similar expression profiles have similar functions in cells …

Protein quality control degradation systems rid the cell of aberrant proteins, preventing
detrimental effects on normal cellular function. Although such systems have been identified …

We used transcriptional profiling to investigate the response of the fungal pathogen Candida
albicans to temperature and osmotic and oxidative stresses under conditions that permitted> …

Large-scale biological networks represent relationships between genes, but our
understanding of how networks are functionally organized is limited. Here, I describe spatial …

We have systematically explored the in vivo occupancy of promoters and open reading
frames by components of the RNA polymerase II transcription initiation and elongation …

In development of yeast cell factories, the adequate stress tolerance of the yeast strains is
the universal requirement for industrial fermentation. Primary stress factor is the end product …

As a well-known phenomenon, total mRNAs poorly correlate to proteins in their abundances
as reported. Recent findings calculated with bivariate models suggested even poorer such …