A common need for microbial cells is the ability to respond to potentially toxic environmental
insults. Here we review the progress in understanding the response of the yeast …

Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology …

Protein activity is the ultimate arbiter of function in most cellular pathways, and protein
concentration is fundamentally connected to protein action. While the proteome of yeast has …

Abstract Superoxide dismutase 1 (Sod1) has been known for nearly half a century for
catalysis of superoxide to hydrogen peroxide. Here we report a new Sod1 function in …

▪ Abstract Several reactive oxygen species (ROS) are continuously produced in plants as
byproducts of aerobic metabolism. Depending on the nature of the ROS species, some are …

Hypotheses The drive to survive is a biological universal. Intelligent behaviour is usually
recognized when individual organisms including plants, in the face of fiercely competitive or …

Determining the effect of gene deletion is a fundamental approach to understanding gene
function. Conventional genetic screens exhibit biases, and genes contributing to a …

Presenting a multidisciplinary perspective in a concise format, Principles of Ecotoxicology,
Third Edition discusses the fundamental chemical and ecological nature of pollution …

We have determined how most of the transcriptional regulators encoded in the eukaryote
Saccharomyces cerevisiae associate with genes across the genome in living cells. Just as …

Molecular oxygen (O2) is the premier biological electron acceptor that serves vital roles in
fundamental cellular functions. However, with the beneficial properties of O2 comes the …