The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by …

This article discusses the role of the lateral hypothalamic area (LHA) in feeding and drinking
and draws on data obtained from lesion and stimulation studies and neurochemical and …

Hypocretin (orexin) is synthesized by neurons in the lateral hypothalamus and has been
reported to increase food intake and regulate the neuroendocrine system. In the present …

A new orexigenic peptide called hypocretin (orexin) has recently been described in neurons
of the lateral hypothalamus and perifornical area. The medial and lateral hypothalamus …

Hypocretin (orexin) has recently been shown to increase feeding when injected into the
brain. Using both rat and primate brains, we tested the hypothesis that a mechanism of …

This article reviews findings that have accumulated since the original description of the
syndrome that follows destruction of the lateral hypothalamic area (LHA). These data …

Increased motivation for highly rewarding food is a major contributing factor to obesity. Most
of the literature focuses on the mesolimbic nuclei as the core of reward behavior regulation …

Ghrelin is a stomach-produced hormone that stimulates ingestive behavior and increases
motivated behavior to obtain palatable foods. Ghrelin receptors (growth hormone …

The orexigenic peptides hypocretin (orexin) and melanin‐concentrating hormone (MCH) are
involved in the control of food intake and in other homeostatic functions including sleep and …

The pro-inflammatory role of interleukin-6 (IL-6) is well-characterized. Blockade of IL-6, by
Tocilizumab, is used in patients with rheumatoid arthritis and those diagnosed with cytokine …