Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae, a well-known Chinese
medicinal herb that presents anticancer effects in various types of cancer cell lines. In this …

Tumor dormancy refers to a critical stage in cancer development in which tumor cells remain
occult for a prolonged period of time until they eventually progress and become clinically …

Background: Tumor hypoxia is a paradigmatic negative prognosticator of treatment
resistance in Head and Neck Squamous Cell Carcinoma (HNSCC). The lack of robust and …

Background The interaction between tumor cells and their immunosuppressive
microenvironment promotes tumor progression and drug resistance. Thus, simultaneously …

Tumour formation is dependent on nutrient and oxygen supply from adjacent blood vessels.
Angiogenesis inhibitors can play a vital role in controlling blood vessel formation and …

Honokiol, widely known as an antitumor agent, has been used as an antiangiogenesis drug
lead. In this paper, 47 honokiol analogues and derivatives were investigated for their …

Increasing numbers of cancer deaths worldwide demand for new treatment avenues. Cold
physical plasma is a partially ionized gas expelling a variety of reactive oxygen and nitrogen …

In endothelial cells, binding of vascular endothelial growth factor (VEGF) to the receptor
VEGFR2 activates multiple signaling pathways that trigger processes such as proliferation …

Prostate cancer remains a significant public health problem, with limited therapeutic options
in the setting of castrate-resistant metastatic disease. Angiogenesis inhibition is a relatively …

The prognosis of patients suffering from advanced‐stage head and neck squamous cell
carcinoma (HNSCC) remains poor. Medical gas plasma therapy receives growing attention …