Genetics of developmental dyslexia

TS Scerri, G Schulte-Körne - European child & adolescent psychiatry, 2010 - Springer
Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in
school-aged children. Linkage studies have identified numerous loci throughout the genome …

Molecular genetics of dyslexia: an overview

A Carrion‐Castillo, B Franke, SE Fisher - Dyslexia, 2013 - Wiley Online Library
Dyslexia is a highly heritable learning disorder with a complex underlying genetic
architecture. Over the past decade, researchers have pinpointed a number of candidate …

Understanding the complex etiologies of developmental disorders: behavioral and molecular genetic approaches

EG Willcutt, BF Pennington, L Duncan… - … of Developmental & …, 2010 - journals.lww.com
Objective: This article has 2 primary goals. First, a brief tutorial on behavioral and molecular
genetic methods is provided for readers without extensive training in these areas. To …

[HTML][HTML] Distinct and overlapping roles for AP-1 and GGAs revealed by the “knocksideways” system

J Hirst, GHH Borner, R Antrobus, AA Peden… - Current Biology, 2012 - cell.com
Although adaptor protein complex 1 (AP-1) and Golgi-localized, γ ear-containing, ADP-
ribosylation factor-binding proteins (GGAs) are both adaptors for clathrin-mediated …

Genetic and environmental risk factors for developmental dyslexia in children: Systematic review of the last decade

N Becker, M Vasconcelos, V Oliveira… - Developmental …, 2017 - Taylor & Francis
Despite advances in the characterization of developmental dyslexia (DD), several questions
regarding the interplay between DD-susceptibility genes and environmental risk factors …

Adeno-associated virus 2 bound to its cellular receptor AAVR

R Zhang, L Cao, M Cui, Z Sun, M Hu, R Zhang… - Nature …, 2019 - nature.com
Adeno-associated virus (AAV) is a leading vector for virus-based gene therapy. The receptor
for AAV (AAVR; also named KIAA0319L) was recently identified, and the precise …

A theoretical molecular network for dyslexia: integrating available genetic findings

G Poelmans, JK Buitelaar, DL Pauls, B Franke - Molecular psychiatry, 2011 - nature.com
Developmental dyslexia is a common specific childhood learning disorder with a strong
heritable component. Previous studies using different genetic approaches have identified …

Genome‐wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders

KM Price, KG Wigg, Y Feng, K Blokland… - Genes, Brain and …, 2020 - Wiley Online Library
Reading disabilities (RD) are the most common neurocognitive disorder, affecting 5% to
17% of children in North America. These children often have comorbid neurodevelopmental …

The neuronal migration hypothesis of dyslexia: A critical evaluation 30 years on

LG Guidi, A Velayos‐Baeza… - European Journal of …, 2018 - Wiley Online Library
The capacity for language is one of the key features underlying the complexity of human
cognition and its evolution. However, little is known about the neurobiological mechanisms …

[HTML][HTML] The polygenic nature and complex genetic architecture of specific learning disorder

M Georgitsi, I Dermitzakis, E Soumelidou, E Bonti - Brain sciences, 2021 - mdpi.com
Specific Learning Disorder (SLD) is a multifactorial, neurodevelopmental disorder which
may involve persistent difficulties in reading (dyslexia), written expression and/or …