In chronic infections and in cancer, persistent antigen stimulation under suboptimal
conditions can lead to the induction of T-cell exhaustion. Exhausted T cells are …

abstract Despite significant research efforts, only a few treatment approaches have been
developed for hepatocellular carcinoma (HCC). In recent years, immune checkpoint …

Ferroptosis is an iron-dependent cell death process that plays important regulatory roles in
the occurrence and development of cancers, including hepatocellular carcinoma (HCC) …

Chronic hepatitis B virus (HBV) infection is one of the high-risk factors for human HCC.
Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation …

Objectives To investigate the predictive value of quantifiable imaging and inflammatory
biomarkers in patients with hepatocellular carcinoma (HCC) for the clinical outcome after …

Simple Summary Infections with Hepatitis B and Hepatitis C viruses are usually
asymptomatic and although some patients undergo resolution of infection, the majority do …

Simple Summary The immunosuppressive microenvironment is closely related to the poor
prognosis of patients with PDAC. Tfh cells play an anti-tumor function in various malignant …

Background: Lung cancer is the most life-threatening cancer type worldwide. Treatment
options include surgery, radio-and chemotherapy, as well as the use of immunomodulatory …

Background & Aims Immune checkpoint inhibitors have some efficacy in the treatment of
hepatocellular carcinoma (HCC). Programmed cell death 1 ligand 1 (PD-L1), expressed on …

Non-alcoholic fatty liver disease (NAFLD) and Hepatitis B virus infection (HBV) constitute
common chronic liver diseases with worldwide distribution. NAFLD burden is expected to …