Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various
inflammatory conditions as well as for cancer. Despite its widespread use, there is a paucity …

Inflammation plays a pivotal role in the ischemia/reperfusion (I/R) injury. Inflammatory
response is initiated by the detection of pathogen-associated molecular patterns and/or …

Background Oxidative stress and muscle damage occur during exhaustive bouts of exercise,
and many runners report pain and soreness as major influences on changes or breaks in …

Inflammasomes are multiprotein intracellular complexes composed of innate immune
system receptors and sensors; they activate the inflammatory cascade in response to …

The number of diabetic patients in Europe and world-wide is growing. Diabetes confers a 2-
fold higher risk for vascular disease. Lack of insulin production (Type 1 diabetes, T1D) or …

Neuroinflammation, characterized by the activation of glial cells, is a hallmark in several
neurological and neurodegenerative disorders. Inadequate inflammation cannot eliminate …

Abstract Background Water dropwort (Oenanthe javanica), an umbelliferous plant, has been
reported as hypolipidemic, antiplatelet, antitumor, or immune-stimulating agents and it has …

The contribution of astrocytes and microglia to the regulation of neuroplasticity or
neurovascular unit (NVU) is based on the coordinated secretion of gliotransmitters and …

The impact of circadian rhythms on cardiovascular function and disease development is well
established, with numerous studies in genetically modified animals emphasizing the …

Methylene blue (MB), which has antioxidant, anti-inflammatory, neuroprotective, and
mitochondria protective effects, has been widely used as a dye and medication. However …