Advances in understanding CO2 responsive plant metabolomes in the era of climate change

BB Misra, S Chen - Metabolomics, 2015 - Springer
Anthropogenic climate change due to increased CO 2 emission poses a major threat to
global crop productivity, food quality, and security. Numerous studies, mostly classical, have …

Metabolic adaptation of intracellular bacteria and fungi to macrophages

M Sprenger, L Kasper, M Hensel, B Hube - International Journal of Medical …, 2018 - Elsevier
The mature phagosome of macrophages is a hostile environment for the vast majority of
phagocytosed microbes. In addition to active destruction of the engulfed microbes by …

Intracellular Mycobacterium leprae utilizes host glucose as a carbon source in Schwann cells

K Borah, KCV Girardi, TA Mendum, LMS Lery… - MBio, 2019 - Am Soc Microbiol
New approaches are needed to control leprosy, but understanding of the biology of the
causative agent Mycobacterium leprae remains rudimentary, principally because the …

The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

M Beyß, S Azzouzi, M Weitzel, W Wiechert… - Frontiers in …, 2019 - frontiersin.org
13C metabolic flux analysis (MFA) is the method of choice when a detailed inference of
intracellular metabolic fluxes in living organisms under metabolic quasi-steady state …

Central role of pyruvate kinase in carbon co-catabolism of Mycobacterium tuberculosis

T Noy, O Vergnolle, TE Hartman, KY Rhee… - Journal of Biological …, 2016 - ASBMB
Mycobacterium tuberculosis (Mtb) displays a high degree of metabolic plasticity to adapt to
challenging host environments. Genetic evidence suggests that Mtb relies mainly on fatty …

A systematic evaluation of Mycobacterium tuberculosis Genome-Scale Metabolic Networks

VA López-Agudelo, TA Mendum, E Laing… - PLoS Computational …, 2020 - journals.plos.org
Metabolism underpins the pathogenic strategy of the causative agent of TB, Mycobacterium
tuberculosis (Mtb), and therefore metabolic pathways have recently re-emerged as attractive …

Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection

C Trujillo, A Blumenthal, J Marrero, KY Rhee… - MBio, 2014 - Am Soc Microbiol
Triosephosphate isomerase (TPI) catalyzes the interconversion of dihydroxyacetone
phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). This reaction is required for …

[HTML][HTML] l-Histidine, arachidonic acid, biliverdin, and l-cysteine-glutathione disulfide as potential biomarkers for cured pulmonary tuberculosis

WJ Yi, YS Han, LL Wei, LY Shi, H Huang… - Biomedicine & …, 2019 - Elsevier
Lack of laboratory standards for cured tuberculosis (TB) can lead to early discharge of
untreated TB patients from the hospital, resulting in increased risk of TB spread and of …

Metabolic regulation and coordination of the metabolism in bacteria in response to a variety of growth conditions

K Shimizu - … engineering research and industrial applications I: cell …, 2016 - Springer
<? xm-replace_text {Heading}?> Abstract Living organisms have sophisticated but well-
organized regulation system. It is important to understand the metabolic regulation …

Metabolism of myo-Inositol by Legionella pneumophila Promotes Infection of Amoebae and Macrophages

C Manske, U Schell, H Hilbi - Applied and environmental …, 2016 - Am Soc Microbiol
Legionella pneumophila is a natural parasite of environmental amoebae and the causative
agent of a severe pneumonia termed Legionnaires' disease. The facultative intracellular …