In vivo and in vitro postovulatory aging: when time works against oocyte quality?
V Di Nisio, S Antonouli, P Damdimopoulou… - Journal of Assisted …, 2022 - Springer
In mammalian species an optimal fertilization window during which successful fertilization
occurs. In the majority of mammals estrus marks ovulation time and coincident with mating …
occurs. In the majority of mammals estrus marks ovulation time and coincident with mating …
N-acetyl-cysteine and the control of oxidative stress during in vitro ovarian follicle growth, oocyte maturation, embryo development and cryopreservation
LG Barrozo, LRFM Paulino, BR Silva… - Animal Reproduction …, 2021 - Elsevier
Oxidative stress is generated by an imbalance between reactive oxygen species (ROS)
formation and cellular defense mechanisms. To reduce cellular damage caused by ROS in …
formation and cellular defense mechanisms. To reduce cellular damage caused by ROS in …
Oxidative stress and reproductive function: oxidative stress and in vitro ageing of the post-ovulatory oocyte: an update on recent advances in the field
In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …
abnormalities in offspring. This review provides an update on the contributions of oxidative …
[HTML][HTML] Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs
YJ Niu, W Zhou, ZW Nie, D Zhou, YN Xu, SA Ock… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Ubiquinol-10, the reduced form of coenzyme Q10, protects mammalian cells from oxidative
damage and enhances mitochondrial activity. However, the protective effect of ubiquinol-10 …
damage and enhances mitochondrial activity. However, the protective effect of ubiquinol-10 …
[HTML][HTML] N-acetyl-L-cysteine (NAC) delays post-ovulatory oocyte aging in mouse
Y Wang, L Li, LH Fan, Y Jing, J Li, YC Ouyang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The quality of post-ovulatory oocytes decreases with aging. In this study, we aimed to
investigate the effects of N-acetyl-L-cysteine (NAC), a broadly used antioxidant, on oocyte …
investigate the effects of N-acetyl-L-cysteine (NAC), a broadly used antioxidant, on oocyte …
Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes
T Trapphoff, M Heiligentag, D Dankert… - Human …, 2016 - academic.oup.com
STUDY QUESTION Is the postovulatory aging-dependent differential decrease of mRNAs
and polyadenylation of mRNAs coded by maternal effect genes associated with altered …
and polyadenylation of mRNAs coded by maternal effect genes associated with altered …
[HTML][HTML] Epigallocatechin-3-gallate protects porcine oocytes against post-ovulatory aging through inhibition of oxidative stress
D Zhou, MH Sun, WJ Jiang, XH Li, SH Lee… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Increased levels of oxidative stress are major factors that drive the process of post-ovulatory
oocyte aging. Epigallocatechin-3-gallate (EGCG), which accounts for up to 50% of the …
oocyte aging. Epigallocatechin-3-gallate (EGCG), which accounts for up to 50% of the …
[HTML][HTML] Nitric oxide-induced protein S-nitrosylation causes mitochondrial dysfunction and accelerates post-ovulatory aging of oocytes in cattle
YJ Niu, D Zhou, W Zhou, ZW Nie, JY Kim… - Journal of Animal …, 2020 - e-jarb.org
Nitric oxide (NO)-induced protein S-nitrosylation triggers mitochondrial dysfunction and was
related to cell senescence. However, the exact mechanism of these damages is not clear. In …
related to cell senescence. However, the exact mechanism of these damages is not clear. In …
β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs
L Li, Q Han, Y Chen, M Zhang, L Wang, X An, S Zhang… - Plos one, 2023 - journals.plos.org
Oocyte senescence alters the shape and function, thereby weakening the fertilization
potential. Nicotinamide mononucleotide (NMN) reverses age-related dysfunctions in various …
potential. Nicotinamide mononucleotide (NMN) reverses age-related dysfunctions in various …
N-乙酰半胱氨酸缓解母猪夏季热应激的初报
程玲华， 薛振华， 齐鑫， 刘瀛蔚， 吴中红， 安磊， 云鹏… - 黑龙江动物繁殖, 2016 - cqvip.com
N-乙酰半胱氨酸(N-acetyl-L-cysteine, NAC) 是一种含有巯基的化合物, 谷胱甘肽的前体物质,
具有清除自由基, 抗氧化, 抗炎, 防止DNA 损伤等作用. 本实验拟在热应激条件下 …
具有清除自由基, 抗氧化, 抗炎, 防止DNA 损伤等作用. 本实验拟在热应激条件下 …