Chronic inflammatory diseases, such as rheumatoid arthritis, steatohepatitis, periodontitis,
chronic kidney disease, and others are associated with an increased risk of atherosclerotic …

After receptor-mediated endocytosis, the intracellular fate of triglyceride-rich lipoproteins
(TRLs) is far more complex than the classical degradation pathway of low-density …

Transforming growth factor-β (TGF-β) plays a pivotal role in a range of biological processes,
including the control of cellular proliferation and differentiation, regulation of tissue repair …

Abstract Background Apolipoprotein E deficiency (ApoE−/−) increases progressively iron in
the liver, spleen and aortic tissues with age in mice. However, it is unknown whether ApoE …

Apolipoprotein E (ApoE) plays a key role in tumorigenesis and progression, such as cell
proliferation, angiogenesis and metastasis. ApoE overexpression was associated with …

Sex differences in coronary artery disease (CAD) presentation, risk factors and prognosis
have been widely studied. Similarly, studies on atherosclerosis have shown prominent sex …

The natural incidence of fatty liver in ruminants is significantly higher than in monogastric
animals. Fatty liver is associated with sterol regulatory element-binding protein 1c (SREBP …

The association between APOE genotypes and cardiovascular disease (CVD) is partially
mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and …

Altered levels of adipokines, derived as a result of distorted adipocytes, are the major factors
responsible for changing biochemical parameters in obesity that leads to the development of …

While most of us live our lives according to the working week, we did not evolve to be bound
by industrial schedules, nor did the food we eat. Despite this, we eat the products of …