Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a
chemically diverse class of metabolites. Many RiPPs show potent biological activities that …

Natural products (NPs) have historically played a primary role in the discovery of small-
molecule drugs. However, due to the advent of other methodologies and the drawbacks of …

Natural products research increasingly applies-omics technologies to guide molecular
discovery. While the combined analysis of genomic and metabolomic datasets has proved …

Sour rot, caused by Geotrichum citri-aurantii, is a major postharvest disease in citrus and
results in significant economic losses. The genus Beauveria is recognized as a promising …

Due to the continued emergence of resistance and a lack of new and promising antibiotics,
bacterial infection has become a major public threat. High-throughput screening (HTS) …

The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …

Covering: up to the end of 2021 Bacterial polycyclic xanthone natural products (BPXNPs)
are a growing family of natural xanthones featuring a pentangular architecture with various …

Although microbial genomes harbor an abundance of biosynthetic gene clusters, there
remain substantial technological gaps that impair the direct correlation of newly discovered …

Recent years have seen a sharp increase in the development of deep learning and artificial
intelligence-based molecular informatics. There has been a growing interest in applying …

Cancer is a global health challenge that remains to be a field of extensive research aiming
to find new anticancer therapeutics. The 20S proteasome complex is one of the targets of …