In this chapter, the mapping of physical–chemical descriptor space of natural products and
its relation to the biological space, with emphasis on evolutionary and topical biological …

Plants represent a vast natural repository of unique and often potent compounds of
pharmaceutical and industrial importance. Opium poppy (Papaver somniferum) is one of the …

Natural products (NPs) include crude drugs, extracts, botanicals and pure compounds
obtained from nature. NPs offer a rich source of diverse biologically active compounds with …

Natural products are a historically valuable source of drugs. Their unique features such as
evolutionary selection to possess biological activity and complementarity of chemical space …

Organic chemists love to make molecules. During much of our history, this activity was target-
driven and focused on making compounds one at a time with exact precision. In the last 20 …

Metabolite profiling has been carried out for decades and is as such not a new research
area. However, the field has attracted increasing attention in the last couple of years, and the …

Firstly, I am deeply grateful to the almighty God “Allah” for letting me through all the
difficulties. Then, I would like to express my thanks to many people who have helped me …

My deep earnest appreciation, first and foremost, is to God, the author of all wisdom,
knowledge and understanding for the benefit and grace to run the Ph. D. programme to …

A chemoselective Dieckmann ring closure using an oxazolidine derived from serine may be
used to generate a tetramic acid, the further manipulation of which by reduction and ring …

Solid-phase syntheses of combinatorial libraries based on natural products, such as,(i)
vitamin D3,(ii) macrosphelide A,(iii) aurilide,(iv) aeruginosin 298-A,(v) trisaccharides,(vi) …