Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International Journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …

Molecular Mechanism Operating in Animal Models of Neurogenic Detrusor Overactivity: A Systematic Review Focusing on Bladder Dysfunction of Neurogenic Origin

A Ferreira, D Nascimento, CD Cruz - International Journal of Molecular …, 2023 - mdpi.com
Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder,
characterized by urinary urgency, retention, and incontinence, as a result of a neurologic …

Acute ampakines increase voiding function and coordination in a rat model of SCI

S Rana, F Alom, RC Martinez, DD Fuller, AD Mickle - Elife, 2024 - elifesciences.org
Neurogenic bladder dysfunction causes urological complications and reduces the quality of
life in persons with spinal cord injury (SCI). Glutamatergic signaling via AMPA receptors is …

Assessing Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury: Animal Models in Preclinical Neuro-Urology Research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Impact of Endurance Training on Regeneration of Axons, Glial Cells, and Inhibitory Neurons after Spinal Cord Injury: A Link between Functional Outcome and …

K Kiss Bimbova, M Bacova, A Kisucka, J Gálik… - International Journal of …, 2023 - mdpi.com
Endurance training prior to spinal cord injury (SCI) has a beneficial effect on the activation of
signaling pathways responsible for survival, neuroplasticity, and neuroregeneration. It is …

Potential Roles of Specific Subclasses of Premotor Interneurons in Spinal Cord Function Recovery after Traumatic Spinal Cord Injury in Adults

A Dominguez-Bajo, F Clotman - Cells, 2024 - mdpi.com
The differential expression of transcription factors during embryonic development has been
selected as the main feature to define the specific subclasses of spinal interneurons …

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic …

W Qu, X Wu, W Wu, Y Wang, Y Sun, L Deng… - Neural Regeneration … - journals.lww.com
Schwann cell transplantation is considered one of the most promising cell-based therapy to
repair injured spinal cord due to its unique growth-promoting and myelin-forming properties …