Strengthening Laboratory Systems for Ensuring Accurate Diagnoses in Mother-to-Child Transmission (MTCT) Prevention Programs in Uganda: A Narrative Review

EI Obeagu, GU Obeagu - Annals of Medicine and Surgery, 2024 - journals.lww.com
Mother-to-child transmission (MTCT) of HIV remains a significant public health challenge in
Uganda, necessitating a focused examination of the state of laboratory systems to ensure …

Dolutegravir resistance in sub-Saharan Africa: should resource-limited settings be concerned for future treatment?

D Kamori, G Barabona - Frontiers in Virology, 2023 - frontiersin.org
In sub-Saharan Africa (SSA) the burden of non-nucleoside reverse transcriptase inhibitor
(NNRTI) HIV drug resistance (HIVDR) has been high over the years. Therefore, in 2018 the …

Trends Analysis of HIV Infection and Antiretroviral Treatment Outcome in Amhara Regional from 2015 to 2021, Northeast Ethiopia

T Addisu, M Tilahun, S Wedajo… - HIV/AIDS-Research and …, 2023 - Taylor & Francis
Background The persistent efforts of HIV/AIDS epidemiology remain one of the world's most
important community health threats. To avoid becoming an epidemic, UNAIDS has set three …

Antiretroviral treatment-induced galectin-9 might impact HIV viremia in addition to contributing to inflammaging

A Shete, V Wagh, J Sawant, P Shidhaye… - International Journal of …, 2023 - mdpi.com
Background: Galectin-9 induces HIV reactivation and also contributes to non-AIDS events
through inflammaging. Hence, it is important to assess its levels in HIV-infected individuals …

Long-term HIV care outcomes under universal HIV treatment guidelines: A retrospective cohort study in 25 countries

E Brazier, O Tymejczyk, K Wools-Kaloustian… - PLoS …, 2024 - journals.plos.org
Background While national adoption of universal HIV treatment guidelines has led to
improved, timely uptake of antiretroviral therapy (ART), longer-term care outcomes are …

Left behind on the path to 90‐90‐90: understanding and responding to HIV among displaced people

TI Vasylyeva, I Bojorquez, MD Pham - African Journal of …, 2022 - journals.lww.com
Introduction: In 2021, the number of people affected by displacement worldwide reached the
highest on record, with an estimated 30.5 million refugees and 4.6 million asylum seekers …

Point-of-care viral load testing to manage HIV viremia during the rollout of dolutegravir-based ART in South Africa: a randomized feasibility study (POwER)

J Dorward, Y Sookrajh, R Lessells, E Bulo… - JAIDS Journal of …, 2023 - journals.lww.com
Background: Data are required regarding the feasibility of conducting a randomized trial of
point-of-care viral load (VL) testing to guide management of HIV viremia and to provide …

Field performance and cost‐effectiveness of a point‐of‐care triage test for HIV virological failure in Southern Africa

A Saura‐Lázaro, P Bock, E Bogaart… - Journal of the …, 2023 - Wiley Online Library
Introduction Antiretroviral therapy (ART) monitoring using viral load (VL) testing is
challenging in high‐burden, limited‐resources settings. Chemokine IP‐10 (interferon …

Optimising HIV drug resistance testing laboratory networks in Kenya: insights from systems engineering modelling

Y Wang, L Kingwara, AD Wagner, N Yongo… - BMJ open, 2024 - bmjopen.bmj.com
Background HIV drug resistance (DR) is a growing threat to the durability of current and
future HIV treatment success. DR testing (DRT) technologies are very expensive and …

Geospatial and temporal mapping of detectable HIV-1 viral loads amid dolutegravir rollout in KwaZulu-Natal, South Africa

L Gounder, A Tomita, R Lessells… - PLOS Global Public …, 2024 - journals.plos.org
South Africa rolled out dolutegravir (DTG) as first-line antiretroviral therapy (ART) in
December 2019 to overcome high rates of pretreatment non-nucleoside reverse …