Macrophages are important immune cells in innate immunity, and have remarkable
heterogeneity and polarization. Under pathological conditions, in addition to the resident …

The liver communicates with the intestine via the portal vein, biliary system, and mediators in
the circulation. Microbes in the intestine maintain liver homeostasis but can also serve as a …

Background/aims Whereas nonalcoholic fatty liver disease (NAFLD) is a multisystem
disease, the association between metabolic dysfunction-associated fatty liver disease …

中国人群的肝癌存在生存率低, 死亡率高的情况, 如何有效降低肝癌相关负担仍是中国公共卫生
和慢性病防控领域亟待解决的重大问题, 而肝癌人群筛查策略优化是值得持续探索的重要抓手和 …

Fatty liver disease associated with metabolic dysfunction is of increasing concern in
mainland China, the world's most populous country. The incidence of fatty liver disease is …

Background & Aims Antiviral therapy improves the clinical outcomes of patients with chronic
hepatitis B (CHB), including those with cirrhosis. In the present study, we validated the …

Abstract Background Coronavirus disease 2019 (COVID-19) is an infectious disease
characterized by cough, fever, and fatigue and 20% of cases will develop into severe …

This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …

During liver fibrogenesis, liver sinusoidal capillarization and extracellular matrix (ECM)
deposition construct dual pathological barriers to drug delivery. Upon capillarization, the …

Background Heavy metals entering the human body could cause damage to a variety of
organs. However, the combined harmful effects of exposure to various metals on liver …