Cardiac fibrosis is a common pathological consequence of most myocardial diseases. It is
associated with the excessive accumulation of extracellular matrix proteins as well as …

Pulmonary fibrosis, a kind of terminal pathological changes in the lung, is caused by
aberrant wound healing, deposition of extracellular matrix (ECM), and eventually …

Vascular dysfunction is a hallmark of chronic diseases in elderly. The contribution of the
vasculature to lung repair and fibrosis is not fully understood. Here, we performed an …

Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease characterized by
myofibroblast accumulation and progressive lung scarring. To identify transcriptional gene …

Mesenchymal cells in the lung are crucial during development, but also contribute to the
pathogenesis of fibrotic disorders, including idiopathic pulmonary fibrosis (IPF), the most …

Although aberrant alveolar myofibroblasts (AMYFs) proliferation and differentiation are often
associated with abnormal lung development and diseases, such as bronchopulmonary …

The last 2 years have presented previously unforeseen challenges in pulmonary medicine.
Despite the significant impact of the SARS‐CoV‐2 pandemic on patients, clinicians and …

Pulmonary fibrosis (PF) is a heterogeneous disease with a poor prognosis. Therefore,
identifying additional therapeutic modalities is required to improve outcome. However, the …

Objective: This study was conducted to establish a rat model of acute exacerbation of
idiopathic pulmonary fibrosis (AE-IPF) using the combination of bleomycin (BLM) and …

Fibrosis has been characterized as a global health problem and ranks as one of the primary
causes of organ dysfunction. Currently, there is no cure for pulmonary fibrosis, and limited …