Asymptomatic hyperuricaemia: a silent activator of the innate immune system
Asymptomatic hyperuricaemia affects~ 20% of the general population in the USA, with
variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered …
variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered …
Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements
Q Li, X Li, J Wang, H Liu, JSW Kwong, H Chen, L Li… - BMJ open, 2019 - bmjopen.bmj.com
Objectives Despite the publication of hundreds of trials on gout and hyperuricemia,
management of these conditions remains suboptimal. We aimed to assess the quality and …
management of these conditions remains suboptimal. We aimed to assess the quality and …
[HTML][HTML] The British Society for Rheumatology guideline for the management of gout
M Hui, A Carr, S Cameron, G Davenport… - …, 2017 - academic.oup.com
Gout is the most common cause of inflammatory arthritis worldwide. In UK general practice,
the overall prevalence has increased from 1.4% in 1999 to 2.49% in 2012 [1], despite the …
the overall prevalence has increased from 1.4% in 1999 to 2.49% in 2012 [1], despite the …
Uric acid as a risk factor for chronic kidney disease and cardiovascular disease―Japanese guideline on the management of asymptomatic hyperuricemia―
I Hisatome, P Li, J Miake, F Taufiq, E Mahati… - Circulation …, 2021 - jstage.jst.go.jp
Serum uric acid (UA) is taken up by endothelial cells and reduces the level of nitric oxide
(NO) by inhibiting its production and accelerating its degradation. Cytosolic and plasma …
(NO) by inhibiting its production and accelerating its degradation. Cytosolic and plasma …
Xanthine oxidase inhibitors for prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
M Bredemeier, LM Lopes, MA Eisenreich… - BMC cardiovascular …, 2018 - Springer
Background Xanthine oxidase inhibitors (XOI), classified as purine-like (allopurinol and
oxypurinol) and non-purine (febuxostat and topiroxostat) XOI, present antioxidant properties …
oxypurinol) and non-purine (febuxostat and topiroxostat) XOI, present antioxidant properties …
Management of gout and hyperuricemia in CKD
AB Vargas-Santos, T Neogi - American Journal of Kidney Diseases, 2017 - Elsevier
Hyperuricemia and gout, the clinical manifestation of monosodium urate crystal deposition,
are common in patients with chronic kidney disease (CKD). Although the presence of CKD …
are common in patients with chronic kidney disease (CKD). Although the presence of CKD …
[PDF][PDF] Pathophysiology of hyperuricemia and its clinical significance–a narrative review
M Skoczyńska, M Chowaniec, A Szymczak… - Reumatologia …, 2020 - termedia.pl
Hyperuricemia, ie increased serum uric acid (UA) concentration, is a common problem in
clinical practice. While there are clear guidelines concerning management of symptomatic …
clinical practice. While there are clear guidelines concerning management of symptomatic …
Use of HLA-B* 58: 01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study
Objective To evaluate the use of prospective screening for the HLA-B* 58: 01 allele to
identify Taiwanese individuals at risk of severe cutaneous adverse reactions (SCARs) …
identify Taiwanese individuals at risk of severe cutaneous adverse reactions (SCARs) …
Treat-to-target (T2T) recommendations for gout
U Kiltz, J Smolen, T Bardin, AC Solal… - Annals of the …, 2017 - ard.bmj.com
Objectives The treat-to-target (T2T) concept has been applied successfully in several
inflammatory rheumatic diseases. Gout is a chronic disease with a high burden of pain and …
inflammatory rheumatic diseases. Gout is a chronic disease with a high burden of pain and …
Three-dimensional nanostructured graphene: synthesis and energy, environmental and biomedical applications
Abstract Three-dimensional (3D) nanostructured graphene can be used as a replacement or
enrichment material. This review presents the types of 3D graphene developed thus far, for …
enrichment material. This review presents the types of 3D graphene developed thus far, for …