Rationale Psychosocial stressors are a well-documented risk factor for mental illness.
Neuroinflammation, in particular elevated microglial activity, has been proposed to mediate …

Many patients with major depressive disorder (MDD) are reported to have higher levels of
multiple inflammatory cytokines including interleukin 6 (IL-6). Recent studies both pre …

Cytokines have been implicated in the pathology of depression. Currently, the evidence is
based on cross-sectional studies and meta-analytic research comparing blood …

High intelligence is touted as being predictive of positive outcomes including educational
success and income level. However, little is known about the difficulties experienced among …

Cytokines are signalling molecules, which play an important role in both immune system
function and brain development and function, and subsequently mental states and …

Stress and recovery from stress significantly affect interactions between the central nervous
system, endocrine pathways and the immune system. However, the influence of acute stress …

The purpose of the present study was to investigate whether ketamine's rapid
antidepressant effects were associated with its anti-inflammatory actions and to explore the …

In major depressive disorder, changes in cytokine levels have been reported to play a role in
pathogenesis. Therefore, we sought to investigate a broad range of cytokines in depression …

Cells of the immune system and the central nervous system are capable of interacting with
each other. The former cell populations respond to infection, tissue injury and trauma by …

Major depressive disorder (MDD) is a common psychiatric disorder effecting approximately
121 million people worldwide and recent reports from the World Health Organization (WHO) …