[HTML][HTML] Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design

Q Qiao, X Liu, T Yang, K Cui, L Kong, C Yang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …

Mesenchymal stem cell-derived extracellular vesicles for the treatment of acute respiratory distress syndrome

A Abraham, A Krasnodembskaya - Stem Cells Translational …, 2020 - academic.oup.com
Acute respiratory distress syndrome (ARDS) is a serious and potentially fatal acute
inflammatory lung condition which currently has no specific treatments targeting its …

[HTML][HTML] A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation

HH Yang, JX Duan, SK Liu, JB Xiong, XX Guan… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Dysregulation of arachidonic acid (ARA) metabolism results in inflammation;
however, its role in acute lung injury (ALI) remains elusive. In this study, we addressed the …

[HTML][HTML] Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury

Y Zhou, P Li, AJ Goodwin, JA Cook, PV Halushka… - Critical Care, 2019 - Springer
Background The acute respiratory distress syndrome (ARDS) is characterized by disruption
of the alveolar-capillary barrier resulting in accumulation of proteinaceous edema and …

[HTML][HTML] Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia

WG Land - Genes & Immunity, 2021 - nature.com
When surveying the current literature on COVID-19, the “cytokine storm” is considered to be
pathogenetically involved in its severe outcomes such as acute respiratory distress …

Mesenchymal stem/stromal cell secretome for lung regeneration: The long way through “pharmaceuticalization” for the best formulation

E Bari, I Ferrarotti, ML Torre, AG Corsico… - Journal of Controlled …, 2019 - Elsevier
Pulmonary acute and chronic diseases, such as chronic obstructive pulmonary disease,
pulmonary fibrosis and pulmonary hypertension, are considered to be major health issues …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome versus classical acute respiratory distress syndrome (a narrative review)

I Krynytska, M Marushchak, I Birchenko… - Iranian journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus, Severe
Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), led to the ongoing global public …

Luteolin regulates the differentiation of regulatory T cells and activates IL‐10‐dependent macrophage polarization against acute lung injury

K Xie, Y Chai, S Lin, F Xu… - Journal of immunology …, 2021 - Wiley Online Library
Objectives. Inflammatory disease characterized by clinical destructive respiratory disorder is
called acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Studies have …

[HTML][HTML] Iron homeostasis in the lungs—a balance between health and disease

J Neves, T Haider, M Gassmann, MU Muckenthaler - Pharmaceuticals, 2019 - mdpi.com
A strong mechanistic link between the regulation of iron homeostasis and oxygen sensing is
evident in the lung, where both systems must be properly controlled to maintain lung …

[HTML][HTML] Acute respiratory distress syndrome

M Diamond, HL Peniston, DK Sanghavi… - StatPearls …, 2023 - ncbi.nlm.nih.gov
Objectives: Describe the etiology of acute respiratory distress syndrome. Outline a patient
presentation consistent with acute respiratory distress syndrome. Identify the parameters …