Blood-based biomarkers for traumatic brain injury: evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory …

FG Strathmann, S Schulte, K Goerl, DJ Petron - Clinical biochemistry, 2014 - Elsevier
Blood-based biomarkers for traumatic brain injury (TBI) have been investigated and
proposed for decades, yet the current clinical assessment of TBI is largely based on clinical …

Hyphenated mass spectrometry techniques for assessing medication adherence: advantages, challenges, clinical applications and future perspectives

S Tanna, J Ogwu, G Lawson - Clinical Chemistry and Laboratory …, 2020 - degruyter.com
Nonadherence to prescribed pharmacotherapy is an understated public health problem
globally and is costing many patients their chance to return to good health and healthcare …

Role of urine drug testing in the current opioid epidemic

G Mahajan - Anesthesia & Analgesia, 2017 - journals.lww.com
While the evidence for urine drug testing for patients on chronic opioid therapy is weak, the
guidelines created by numerous medical societies and state and federal regulatory …

A difficult challenge for the clinical laboratory: accessing and interpreting manufacturer cross-reactivity data for immunoassays used in urine drug testing

JM Reschly-Krasowski… - Academic pathology, 2018 - journals.sagepub.com
Urine drug testing by immunoassay is widely used to detect nonmedical drug use and to
monitor patients prescribed controlled substances. A key attribute of urine drug testing …

Biological Testing and Interpretation of Laboratory Results Associated with Detecting Newborns with Substance Exposure

GA McMillin, AW Morad, JM Boyd… - Clinical …, 2024 - academic.oup.com
Background Substance use during pregnancy is common, as is biological testing that is
intended to help identify prenatal exposures. However, there is no standardized requirement …

Predictive value of positive drug screening results in an urban outpatient population

RL Bertholf, R Sharma… - Journal of Analytical …, 2016 - academic.oup.com
Urine drug testing (UDT) has become an essential component in the management of
patients prescribed opioid analgesics for the treatment of chronic non-malignant pain …

Opiate & benzodiazepine confirmations: to hydrolyze or not to hydrolyze is the question

KL Johnson-Davis - The Journal of Applied Laboratory Medicine, 2018 - academic.oup.com
Background Opiates/opioids and benzodiazepines are commonly prescribed drug therapies
for acute and chronic pain. Urine drug testing is often employed to assess adherence to …

Evaluation of adherence monitoring in buprenorphine treatment: A pilot study using timed drug assays to determine accuracy of testing

N Jamshidi, A Athavale, C Tremonti… - British Journal of …, 2023 - Wiley Online Library
Aims Buprenorphine is effective at reducing relapse to opioid misuse, morbidity and
mortality in opioid‐dependent patients. Urine drug screening (UDS) to assess adherence is …

A new broad-spectrum drug screen for 127 analytes by LC-MS/MS

K Smith, KL Johnson-Davis… - The Journal of Applied …, 2023 - academic.oup.com
Background Broad-spectrum drug screening is offered by many clinical laboratories to
support investigation of possible drug exposures. The traditional broad-spectrum drug …

Demand for interpretation of a urine drug testing panel reflects the changing landscape of clinical needs; opportunities for the laboratory to provide added clinical …

YK Yang, KL Johnson-Davis, BN Kelly… - The journal of applied …, 2020 - academic.oup.com
Background The direct detection of drugs and metabolites in urine using a targeted panel
offers sensitive and specific detection in comparison to the traditional approach to urine drug …