CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …

Background The role of catheter ablation in patients with symptomatic atrial fibrillation and
end-stage heart failure is unknown. Methods We conducted a single-center, open-label trial …

Background The impact of aortic valve replacement (AVR) on progression/regression of
extravalvular cardiac damage and its association with subsequent prognosis is unknown …

Arterial hypertension affects≈ 1 billion people worldwide. It is associated with increased
morbidity and mortality and responsible for millions of deaths each year. Hypertension …

Cardiovascular diseases are the most common cause of worldwide morbidity and mortality,
highlighting the necessity for advanced therapeutic strategies. Ca2+/calmodulin-dependent …

Aims Empagliflozin reduces cardiovascular death (CVD) or heart failure hospitalization
(HHF) in patients with heart failure and preserved ejection fraction (HFpEF). Treatment …

Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

BACKGROUND: Cardiovascular diseases are the main cause of worldwide morbidity and
mortality, highlighting the need for new therapeutic strategies. Autophosphorylation and …

Heart failure and atrial fibrillation (AF) are growing cardiovascular disease epidemics
worldwide. Heart failure with left-ventricular systolic dysfunction (LVSD) can be found in …